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Kcnab3 Gene Detail
Summary
  • Symbol
    Kcnab3
  • Name
    potassium voltage-gated channel, shaker-related subfamily, beta member 3
  • Synonyms
    C330022D06Rik, Kcnab4, mKv(beta)4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336208
    NCBI Gene: 16499
  • Gene Overview
    MyGene.info: KCNAB3
Location & Maps
more
  • Sequence Map
    Chr11:69326258-69333042 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6785 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 42.51 cM, cytoband B4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    KCNAB3, potassium voltage-gated channel subfamily A regulatory beta subunit 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KCNAB3, potassium voltage-gated channel subfamily A regulatory beta subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AKR6A9, KCNA3.1B, KCNA3B, KV-BETA-3
  • Links
    NCBI Gene ID: 9196
    neXtProt AC: NX_O43448

  • Chr Location
    17p13.1; chr17:7921859-7929435 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Kcnab3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005965 VEGA Gene Model | MGI Sequence Detail 6785 C57BL/6J ±  kb
transcript OTTMUST00000013319 VEGA | MGI Sequence Detail 2538 Not Applicable  
polypeptide OTTMUSP00000006169 VEGA | MGI Sequence Detail 404 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    65 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000009253 voltage-gated potassium channel subunit beta-3
  • InterPro Domains
    IPR001395 Aldo/keto reductase/potassium channel subunit beta
    IPR023210 NADP-dependent oxidoreductase domain
    IPR005983 Potassium channel, voltage-dependent, beta subunit, KCNAB
    IPR005402 Potassium channel, voltage-dependent, beta subunit, KCNAB3
    IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related
Molecular
Reagents
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  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-38198, MGI:109154, MGI:2442514
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:36040 Fink M, et al., A new K+ channel beta subunit to specifically enhance Kv2.2 (CDRK) expression. J Biol Chem. 1996 Oct 18;271(42):26341-8
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory