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Sumo3 Gene Detail
Summary
  • Symbol
    Sumo3
  • Name
    small ubiquitin-like modifier 3
  • Synonyms
    2810014B19Rik, D10Ertd345e, SMT3A, Smt3h1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336201
    NCBI Gene: 20610
  • Gene Overview
    MyGene.info: SUMO3
Location & Maps
more
  • Sequence Map
    Chr10:77606097-77641543 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      35447 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    6 experiments
Homology
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  • Human Ortholog
    SUMO3, small ubiquitin-like modifier 3
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SUMO3, small ubiquitin-like modifier 3
    Orthology source: HomoloGene
  • Synonyms
    SMT3A, Smt3B, SMT3H1, SUMO-3
  • Links
    NCBI Gene ID: 6612
    neXtProt AC: NX_P55854

  • Chr Location
    21q22.3; chr21:44805617-44818129 (-)  GRCh38.p2

Human Diseases
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  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    25 phenotype references
  • All Mutations and Alleles
    59
  • Chemically induced (other)
    1
  • Gene trapped
    51
  • Targeted
    7
  • Genomic Mutations
    4 involving Sumo3
  • Incidental Mutations
    APF , CvDC
Mice homozygous for a null allele are viable and fertile and exhibit no phenotypic abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020927 VEGA Gene Model | MGI Sequence Detail 35447 C57BL/6J ±  kb
transcript OTTMUST00000049475 VEGA | MGI Sequence Detail 487 Not Applicable  
polypeptide OTTMUSP00000055307 VEGA | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    137 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • InterPro Domains
    IPR022617 Rad60/SUMO-like domain
    IPR027218 Small ubiquitin-related modifier, chordates
    IPR000626 Ubiquitin domain
    IPR029071 Ubiquitin-related domain
Molecular
Reagents
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  • All nucleic 215
    Genomic 16
    cDNA 194
    Primer pair 4
    Other 1

    Microarray probesets 4
Other
Accession IDs
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MGI:1196330, MGI:1914744, MGI:2143471, MGI:2143812, MGI:2143846
References
more
  • Summaries
    All 51
    Developmental Gene Expression 10
    Diseases 2
    Gene Ontology 5
    Phenotypes 25
  • Earliest
    J:52082 Cole SE, et al., A cluster of keratin-associated proteins on mouse chromosome 10 in the region of conserved linkage with human chromosome 21. Genomics. 1998 Dec 15;54(3):437-42
  • Latest
    J:217019 Wang L, et al., SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development. EMBO Rep. 2014 Aug;15(8):878-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory