Car11
Gene Detail

Symbol Name ID

Car11 carbonic anhydrase 11 MGI:1336193

Synonyms

CA-RP XI

Feature Type

protein coding gene

Genetic Map

Chromosome 7

29.44 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:45699843-45704682 bp, + strand From VEGA annotation of GRCm38   4840 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:36061  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: carbonate dehydratase
Gene Tree: Car11

Human homologs

Human Homolog		CA11, carbonic anhydrase XI
NCBI Gene ID		770
neXtProt AC		NX_O75493
Human Synonyms		CARPX1
Human Chr (Location)		19q13.3; chr19:49141272-49149451 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (4 annotations)

Process	biological_process
Component	basolateral plasma membrane, extracellular region

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (203)    Tissues (104)    Images (55)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	203

cDNA source data(23)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) cDNA(23) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000031338 (Evidence)
Ensembl Gene Model	ENSMUSG00000003273 (Evidence)
Entrez Gene	12348 (Evidence)
UniGene	27736
DFCI	TC1580780
DoTS	DT.485190
NIA Mouse Gene Index	U159955
Consensus CDS Project	CCDS21259.1
International Mouse Knockout Project Status	Car11

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031338	VEGA Gene Model | MGI Sequence Detail	4840	C57BL/6J
transcript	OTTMUST00000077635	VEGA | MGI Sequence Detail	1585	Not Applicable
polypeptide	OTTMUSP00000041110	VEGA | MGI Sequence Detail	328	Not Applicable

All sequences(26) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(35 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001148	Alpha carbonic anhydrase
InterPro	IPR023561	Carbonic anhydrase, alpha-class
InterPro	IPR018348	Carbonic anhydrase-related protein, CA-XI-like, mammal
Protein Ontology	PR:000004914	carbonic anhydrase-related protein 11

References

(Earliest) J:52003 Lovejoy DA, et al., Evolutionarily conserved, acatalytic carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3. Genomics. 1998 Dec 15;54(3):484-93
(Latest) J:193048 Wu L, et al., A systematic survey of carbonic anhydrase mRNA expression during Mammalian inner ear development. Dev Dyn. 2013 Mar;242(3):269-80
All references(32)