Agpat3
Gene Detail

Symbol Name ID

Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 MGI:1336186

Synonyms

D10Jhu12e, LPAAT3

Feature Type

protein coding gene

Genetic Map

Chromosome 10

39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr10:78269178-78352489 bp, - strand From VEGA annotation of GRCm38   83312 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10591  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: 1-acyl-sn-glycerol-3-phosphate acyltransferase-like protein
Gene Tree: Agpat3

Human homologs

Human Homolog		AGPAT3, 1-acylglycerol-3-phosphate O-acyltransferase 3
NCBI Gene ID		56894
neXtProt AC		NX_Q9NRZ7
Human Synonyms		LPAAT3, LPAAT-GAMMA1
Human Chr (Location)		21q22.3; chr21:43865149-43987594 (+)  GRCh38

Alleles and phenotypes

All alleles(14) : Gene trapped(12) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	lipid metabolic process, metabolic process, ...
Component	endoplasmic reticulum, integral component of membrane, ...
Function	1-acylglycerol-3-phosphate O-acyltransferase activity, transferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (7 records)

Data Summary: Results (195)    Tissues (157)    Images (31)
Theiler Stages: 13, 15, 17, 19, 20, 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	177
RT-PCR	18

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(25) Genomic(8) cDNA(14) Primer pair(2) Other(1)
Microarray probesets(8)

Other database links

VEGA Gene Model	OTTMUSG00000020522 (Evidence)
Ensembl Gene Model	ENSMUSG00000001211 (Evidence)
Entrez Gene	28169 (Evidence)
DFCI	TC1575083, TC1608769
DoTS	DT.101391274, DT.101391277, DT.522213, DT.530677, DT.99841351
NIA Mouse Gene Index	U031971
EC	2.3.1.51
Consensus CDS Project	CCDS23963.1
International Mouse Knockout Project Status	Agpat3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020522	VEGA Gene Model | MGI Sequence Detail	83312	C57BL/6J
transcript	OTTMUST00000048657	VEGA | MGI Sequence Detail	5980	Not Applicable
polypeptide	OTTMUSP00000022361	VEGA | MGI Sequence Detail	376	Not Applicable

All sequences(112) RefSeq(22) UniProt(7)

Polymorphisms

SNPs within 2kb(128 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR002123	Phospholipid/glycerol acyltransferase
Protein Ontology	PR:000003836	1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

References

(Earliest) J:53813 Cole SE, et al., High-resolution comparative physical mapping of mouse chromosome 10 in the region of homology with human chromosome 21. Mamm Genome. 1999 Mar;10(3):229-34
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(51)

Other accession IDs

MGI:2143803, MGI:2143842