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Agpat3 Gene Detail
Summary
  • Symbol
    Agpat3
  • Name
    1-acylglycerol-3-phosphate O-acyltransferase 3
  • Synonyms
    D10Jhu12e, LPAAT3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336186
    NCBI Gene: 28169
  • Gene Overview
    MyGene.info: AGPAT3
Location & Maps
more
  • Sequence Map
    Chr10:78269178-78352489 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      83312 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    5 experiments
Homology
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  • Human Ortholog
    AGPAT3, 1-acylglycerol-3-phosphate O-acyltransferase 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AGPAT3, 1-acylglycerol-3-phosphate O-acyltransferase 3
    Orthology source: HomoloGene
  • Synonyms
    LPAAT3, LPAAT-GAMMA1
  • Links
    NCBI Gene ID: 56894
    neXtProt AC: NX_Q9NRZ7

  • Chr Location
    21q22.3; chr21:43865160-43987594 (+)  GRCh38.p2

Human Diseases
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  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    18
  • Chemically induced (other)
    1
  • Gene trapped
    12
  • Targeted
    5
  • Genomic Mutations
    4 involving Agpat3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020522 VEGA Gene Model | MGI Sequence Detail 83312 C57BL/6J ±  kb
transcript OTTMUST00000048657 VEGA | MGI Sequence Detail 5980 Not Applicable  
polypeptide OTTMUSP00000022361 VEGA | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    128 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000003836 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
  • EC
  • InterPro Domains
    IPR032098 Acyltransferase, C-terminal domain
    IPR002123 Phospholipid/glycerol acyltransferase
Molecular
Reagents
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  • All nucleic 25
    Genomic 8
    cDNA 14
    Primer pair 2
    Other 1

    Microarray probesets 8
Other
Accession IDs
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MGI:2143803, MGI:2143842
References
more
  • Summaries
    All 46
    Developmental Gene Expression 7
    Diseases 2
    Gene Ontology 5
    Phenotypes 21
  • Earliest
    J:53813 Cole SE, et al., High-resolution comparative physical mapping of mouse chromosome 10 in the region of homology with human chromosome 21. Mamm Genome. 1999 Mar;10(3):229-34
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory