About   Help   FAQ
Gng12
Gene Detail
Symbol

Name
ID
Gng12
guanine nucleotide binding protein (G protein), gamma 12
MGI:1336171
Synonyms
2010305F15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 6
30.68 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr6:66896397-67021350 bp, + strand
From VEGA annotation of GRCm38

  124954 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32427  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: GNG12
Protein SuperFamily: GTP-binding regulatory protein gamma chain
Gene Tree: Gng12

Human
homologs
GNG12, guanine nucleotide binding protein (G protein), gamma 12
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 55970
neXtProt AC: NX_Q9UBI6

Human Chr (Location): 1p31.3; chr1:67701466-67833779 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(57) : Gene trapped(55) Targeted(2)
Interactions
Gng12 interacts with 316 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process G-protein coupled receptor signaling pathway, signal transduction
Component actin filament, extracellular exosome, ...
Function PDZ domain binding, phosphate ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (71)    Tissues (23)    Images (16)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 71
cDNA source data(183)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase gng12 ; ZFIN gng12a    NEW 
Molecular
reagents
All nucleic(183) cDNA(183)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000022979 (Evidence)
Ensembl Gene Model ENSMUSG00000036402 (Evidence)
Entrez Gene 14701 (Evidence)
UniGene 234342
Consensus CDS Project CCDS39502.1
International Mouse Phenotyping Consortium Status Gng12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022979 VEGA Gene Model | MGI Sequence Detail 124954 C57BL/6J ±  kb
transcript OTTMUST00000055301 VEGA | MGI Sequence Detail 4248 Not Applicable 
polypeptide OTTMUSP00000026466 VEGA | MGI Sequence Detail 72 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(14) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(645 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015898 G-protein gamma-like domain
InterPro IPR001770 G-protein, gamma subunit
Protein Ontology PR:000008105 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
References
(Earliest) J:54663 Downes GB, et al., Chromosomal mapping of five mouse G protein gamma subunits. Genomics. 1999 Apr 1;57(1):173-6
(Latest) J:215128 Moon AM, et al., Disruption of G-protein gamma5 subtype causes embryonic lethality in mice. PLoS One. 2014;9(3):e90970
All references(35)
Other
accession IDs
MGI:1889368, MGI:1889384, MGI:1889807, MGI:1919361, MGI:2141487

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory