About   Help   FAQ
Gng12
Gene Detail
 Symbol
Name
ID
Gng12
guanine nucleotide binding protein (G protein), gamma 12
MGI:1336171
Synonyms 2010305F15Rik
Feature Type protein coding gene
Genetic Map
Chromosome 6
30.68 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr6:66896397-67021350 bp, + strand
From VEGA annotation of GRCm38

  124954 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32427  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: GTP-binding regulatory protein gamma chain
Gene Tree: Gng12

Human
homologs
Human Homolog GNG12, guanine nucleotide binding protein (G protein), gamma 12
NCBI Gene ID 55970
neXtProt AC  NX_Q9UBI6
Human Chr (Location)  1p31.3; chr1:67701466-67833472 (-)  GRCh38
Alleles
and
phenotypes
All alleles(57) : Gene trapped(55) Targeted(2)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process G-protein coupled receptor signaling pathway, signal transduction
Component actin filament, extracellular vesicular exosome, ...
Function PDZ domain binding, phosphate ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (71)    Tissues (23)    Images (16)
Theiler Stages: 23
Assay TypeResults
RNA in situ 71
cDNA source data(183)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(183) cDNA(183)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022979 (Evidence)
Ensembl Gene ModelENSMUSG00000036402 (Evidence)
Entrez Gene14701 (Evidence)
UniGene234342
Consensus CDS ProjectCCDS39502.1
International Mouse Knockout Project StatusGng12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022979 VEGA Gene Model | MGI Sequence Detail 124954 C57BL/6J ±  kb
transcript OTTMUST00000055301 VEGA | MGI Sequence Detail 4248 Not Applicable 
polypeptide OTTMUSP00000026466 VEGA | MGI Sequence Detail 72 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(14) UniProt(1)
Polymorphisms RFLP(1) : SNPs within 2kb(645 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015898 G-protein gamma-like domain
InterPro IPR001770 G-protein, gamma subunit
Protein Ontology PR:000008105 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
References (Earliest) J:54663 Downes GB, et al., Chromosomal mapping of five mouse G protein gamma subunits. Genomics. 1999 Apr 1;57(1):173-6
(Latest) J:195239 Ahmed SM, et al., KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression. J Cell Biol. 2012 Dec 10;199(6):951-67
All references(35)
Other
accession IDs
MGI:1889368, MGI:1889384, MGI:1889807, MGI:1919361, MGI:2141487

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory