Gng12
Gene Detail

Symbol Name ID

Gng12 guanine nucleotide binding protein (G protein), gamma 12 MGI:1336171

Synonyms

2010305F15Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 6

30.68 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr6:66896397-67021350 bp, + strand From VEGA annotation of GRCm38   124954 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:32427  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: GTP-binding regulatory protein gamma chain
Gene Tree: Gng12

Human homologs

Human Homolog		GNG12, guanine nucleotide binding protein (G protein), gamma 12
NCBI Gene ID		55970
neXtProt AC		NX_Q9UBI6
Human Chr (Location)		1p31.3; chr1:68167149-68299155 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(57) : Targeted(2) Gene trapped(55)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	G-protein coupled receptor signaling pathway, signal transduction
Component	actin filament, heterotrimeric G-protein complex, ...
Function	phosphate ion binding, signal transducer activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (71)    Tissues (23)    Images (16)
Theiler Stages: 23

Assay Type	Results
RNA in situ	71

cDNA source data(179)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(179) cDNA(179)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000022979 (Evidence)
Ensembl Gene Model	ENSMUSG00000036402 (Evidence)
Entrez Gene	14701 (Evidence)
UniGene	234342
Consensus CDS Project	CCDS39502.1
International Mouse Knockout Project Status	Gng12

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022979	VEGA Gene Model | MGI Sequence Detail	124954	C57BL/6J
transcript	OTTMUST00000055301	VEGA | MGI Sequence Detail	4248	Not Applicable
polypeptide	OTTMUSP00000026466	VEGA | MGI Sequence Detail	72	Not Applicable

All sequences(62) RefSeq(12) UniProt(1)

Polymorphisms

RFLP(1) : SNPs(570 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR015898	G-protein gamma-like domain
InterPro	IPR001770	G-protein, gamma subunit
Protein Ontology	PR:000008105	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12

References

(Earliest) J:54663 Downes GB, et al., Chromosomal mapping of five mouse G protein gamma subunits. Genomics. 1999 Apr 1;57(1):173-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Other accession IDs

MGI:1889368, MGI:1889384, MGI:1889807, MGI:1919361, MGI:2141487