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Gng12 Gene Detail
Summary
  • Symbol
    Gng12
  • Name
    guanine nucleotide binding protein (G protein), gamma 12
  • Synonyms
    2010305F15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336171
    NCBI Gene: 14701
  • Gene Overview
    MyGene.info: GNG12
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:66896397-67021350 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 30.68 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    643 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1336171
protein coding gene Chr6:66896397-67021361 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030842
protein coding gene Chr6:66864089-66988255 (+)
A/J MGP_AJ_G0030812
protein coding gene Chr6:63986191-64101882 (+)
AKR/J MGP_AKRJ_G0030740
protein coding gene Chr6:65985694-66104403 (+)
BALB/cJ MGP_BALBcJ_G0030823
protein coding gene Chr6:64351097-64476430 (+)
C3H/HeJ MGP_C3HHeJ_G0030889
protein coding gene Chr6:118042335-118158752 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031281
protein coding gene Chr6:68460507-68585875 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028470
protein coding gene Chr6:61161346-61279586 (+)
CAST/EiJ MGP_CASTEiJ_G0029931
protein coding gene Chr6:66273995-66393748 (+)
CBA/J MGP_CBAJ_G0030510
protein coding gene Chr6:71299391-71414714 (+)
DBA/2J MGP_DBA2J_G0030662
protein coding gene Chr6:63640516-63760960 (+)
FVB/NJ MGP_FVBNJ_G0030615
protein coding gene Chr6:63152232-63270614 (+)
LP/J MGP_LPJ_G0030741
protein coding gene Chr6:66786592-66920564 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030650
protein coding gene Chr6:75002600-75124347 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031307
protein coding gene Chr6:65902093-66025426 (+)
PWK/PhJ MGP_PWKPhJ_G0029646
protein coding gene Chr6:62839585-62959191 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029475
protein coding gene Chr6:65472845-65595412 (+)
WSB/EiJ MGP_WSBEiJ_G0030013
protein coding gene Chr6:66220756-66345622 (+)



Homology
more
  • Human Ortholog
    GNG12, G protein subunit gamma 12
  • Vertebrate Orthologs
    11
  • Human Ortholog
    GNG12, G protein subunit gamma 12
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55970
    neXtProt AC: NX_Q9UBI6
    UniProt: Q9UBI6

  • Chr Location
    1p31.3; chr1:67701466-67833779 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036402 Ensembl Gene Model | MGI Sequence Detail 124954 C57BL/6J ±  kb
transcript ENSMUST00000204511 Ensembl | MGI Sequence Detail 739 Not Applicable  
polypeptide ENSMUSP00000145346 Ensembl | MGI Sequence Detail 83 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR015898 G-protein gamma-like domain
    IPR036284 G-protein gamma-like domain superfamily
    IPR001770 G-protein, gamma subunit
Molecular
Reagents
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  • All nucleic 185
    cDNA 185

    Microarray probesets 4
Other
Accession IDs
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MGI:1889368, MGI:1889384, MGI:1889807, MGI:1919361, MGI:2141487
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:54663 Downes GB, et al., Chromosomal mapping of five mouse G protein gamma subunits. Genomics. 1999 Apr 1;57(1):173-6
  • Latest
    J:215128 Moon AM, et al., Disruption of G-protein gamma5 subtype causes embryonic lethality in mice. PLoS One. 2014;9(3):e90970

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory