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Gng12 Gene Detail
Summary
  • Symbol
    Gng12
  • Name
    guanine nucleotide binding protein (G protein), gamma 12
  • Synonyms
    2010305F15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336171
    NCBI Gene: 14701
  • Gene Overview
    MyGene.info: GNG12
Location & Maps
more
  • Sequence Map
    Chr6:66896397-67021350 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      124954 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 30.68 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    GNG12, G protein subunit gamma 12
  • Vertebrate Orthologs
    11
  • Human Ortholog
    GNG12, G protein subunit gamma 12
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 55970
    neXtProt AC: NX_Q9UBI6

  • Chr Location
    1p31.3; chr1:67701466-67833779 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    57
  • Gene trapped
    55
  • Targeted
    2
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022979 VEGA Gene Model | MGI Sequence Detail 124954 C57BL/6J ±  kb
transcript OTTMUST00000141037 VEGA | MGI Sequence Detail 739 Not Applicable  
polypeptide OTTMUSP00000073770 VEGA | MGI Sequence Detail 83 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    643 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000008105 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  • InterPro Domains
    IPR015898 G-protein gamma-like domain
    IPR001770 G-protein, gamma subunit
Molecular
Reagents
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  • All nucleic 183
    cDNA 183

    Microarray probesets 4
Other
Accession IDs
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MGI:1889368, MGI:1889384, MGI:1889807, MGI:1919361, MGI:2141487
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:54663 Downes GB, et al., Chromosomal mapping of five mouse G protein gamma subunits. Genomics. 1999 Apr 1;57(1):173-6
  • Latest
    J:215128 Moon AM, et al., Disruption of G-protein gamma5 subtype causes embryonic lethality in mice. PLoS One. 2014;9(3):e90970

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory