Minpp1
Gene Detail

Symbol Name ID

Minpp1 multiple inositol polyphosphate histidine phosphatase 1 MGI:1336159

Feature Type

protein coding gene

Genetic Map

Chromosome 19

27.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr19:32485769-32515370 bp, + strand From NCBI annotation of GRCm38   29602 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:37980  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: acid phosphatase
Gene Tree: Minpp1

Human homologs

Human Homolog		MINPP1, multiple inositol-polyphosphate phosphatase 1
NCBI Gene ID		9562
neXtProt AC		NX_Q9UNW1
Human Synonyms		HIPER1, MINPP2, MIPP
Human Chr (Location)		10q23; chr10:89264223-89313218 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human MINPP1

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Mice homozygous for a targeted null mutation exhibit no discernable phenotype; mice are viable and fertile with normal chondrocyte and bone development.

 

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Component	endoplasmic reticulum, membrane, ...
Function	acid phosphatase activity, bisphosphoglycerate 3-phosphatase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (126)    Tissues (100)    Images (31)
Theiler Stages: 11, 12, 20, 22, 23, 28

Assay Type	Results
RNA in situ	120
Northern blot	6

cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(15) Genomic(1) cDNA(13) Primer pair(1)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000024896 (Evidence)
Entrez Gene	17330 (Evidence)
DFCI	TC1572164, TC1590786, TC1752423
DoTS	DT.101382930, DT.110834523, DT.492685, DT.60102061, DT.94262604, DT.94262619
NIA Mouse Gene Index	U019370, U059511
EC	3.1.3.62, 3.1.3.80
Consensus CDS Project	CCDS29751.1
International Mouse Knockout Project Status	Minpp1

Sequences

Length	Strain/Species
genomic	17330	NCBI Gene Model | MGI Sequence Detail	29602	C57BL/6J
transcript	NM_010799	RefSeq | MGI Sequence Detail	2619	C57BL/6
polypeptide	Q9Z2L6	UniProt | EBI | MGI Sequence Detail	481	Not Applicable

All sequences(43) RefSeq(2) UniProt(2)

Protein-related information

Resource	ID	Description
InterPro	IPR016274	Histidine acid phosphatase, eukaryotic
InterPro	IPR000560	Histidine phosphatase superfamily, clade-2
Protein Ontology	PR:000010416	multiple inositol polyphosphate phosphatase 1

Graphical View of Protein Domain Structure

References

(Earliest) J:54008 Chi H, et al., Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19. Genomics. 1999 Mar 15;56(3):324-36
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)

Other accession IDs

MGI:2147435