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Minpp1
Gene Detail
Symbol

Name
ID
Minpp1
multiple inositol polyphosphate histidine phosphatase 1
MGI:1336159
Feature Type
protein coding gene
Genetic Map
Chromosome 19
27.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:32485769-32515370 bp, + strand
From NCBI annotation of GRCm38

  29602 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37980  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: MINPP1
Protein SuperFamily: acid phosphatase
Gene Tree: Minpp1

Human
homologs
MINPP1, multiple inositol-polyphosphate phosphatase 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 9562
neXtProt AC: NX_Q9UNW1

Human Synonyms: HIPER1, MINPP2, MIPP

Human Chr (Location): 10q23; chr10:87502792-87553461 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human MINPP1

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted null mutation exhibit no discernable phenotype; mice are viable and fertile with normal chondrocyte and bone development.
 
Interactions
Minpp1 interacts with 147 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process protein dephosphorylation
Component endoplasmic reticulum, extracellular exosome, ...
Function acid phosphatase activity, bisphosphoglycerate 3-phosphatase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (126)    Tissues (100)    Images (31)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 120
Northern blot 6
cDNA source data(61)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase minpp1 ; ZFIN minpp1b    NEW 
Molecular
reagents
All nucleic(66) Genomic(1) cDNA(64) Primer pair(1)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000024896 (Evidence)
Entrez Gene 17330 (Evidence)
UniGene 255116
DFCI TC1572164, TC1590786, TC1752423
DoTS DT.101382930, DT.110834523, DT.492685, DT.60102061, DT.94262604, DT.94262619
NIA Mouse Gene Index U019370, U059511
EC 3.1.3.62, 3.1.3.80
Consensus CDS Project CCDS29751.1
International Mouse Phenotyping Consortium Status Minpp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 17330 NCBI Gene Model | MGI Sequence Detail 29602 C57BL/6J ±  kb
transcript NM_010799 RefSeq | MGI Sequence Detail 2619 C57BL/6 
polypeptide Q9Z2L6 UniProt | EBI | MGI Sequence Detail 481 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(7 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016274 Histidine acid phosphatase, eukaryotic
InterPro IPR000560 Histidine phosphatase superfamily, clade-2
Protein Ontology PR:000010416 multiple inositol polyphosphate phosphatase 1
Graphical View of Protein Domain Structure
References
(Earliest) J:54008 Chi H, et al., Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19. Genomics. 1999 Mar 15;56(3):324-36
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)
Other
accession IDs
MGI:2147435

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory