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Minpp1 Gene Detail
Summary
  • Symbol
    Minpp1
  • Name
    multiple inositol polyphosphate histidine phosphatase 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336159
    NCBI Gene: 17330
  • Gene Overview
    MyGene.info: MINPP1
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:32485769-32515370 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 27.25 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1336159
protein coding gene Chr19:32485769-32515370 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025040
protein coding gene Chr19:31119090-31149718 (+)
A/J MGP_AJ_G0025017
protein coding gene Chr19:29569281-29601240 (+)
AKR/J MGP_AKRJ_G0024985
protein coding gene Chr19:30603318-30634262 (+)
BALB/cJ MGP_BALBcJ_G0025016
protein coding gene Chr19:29621833-29651179 (+)
C3H/HeJ MGP_C3HHeJ_G0024772
protein coding gene Chr19:30596306-30624628 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025457
protein coding gene Chr19:31982509-32015368 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022876
protein coding gene Chr19:29474637-29506522 (+)
CAST/EiJ MGP_CASTEiJ_G0024243
protein coding gene Chr19:30498894-30529401 (+)
CBA/J MGP_CBAJ_G0024750
protein coding gene Chr19:33471745-33507108 (+)
DBA/2J MGP_DBA2J_G0024882
protein coding gene Chr19:29493502-29522636 (+)
FVB/NJ MGP_FVBNJ_G0024844
protein coding gene Chr19:29317925-29347056 (+)
LP/J MGP_LPJ_G0024967
protein coding gene Chr19:31121044-31150068 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024871
protein coding gene Chr19:33330547-33359559 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025512
protein coding gene Chr19:30653171-30685156 (+)
PWK/PhJ MGP_PWKPhJ_G0023991
protein coding gene Chr19:29188977-29217947 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023795
protein coding gene Chr19:29987521-30014734 (+)
WSB/EiJ MGP_WSBEiJ_G0024309
protein coding gene Chr19:30690198-30720629 (+)



Homology
more
  • Human Ortholog
    MINPP1, multiple inositol-polyphosphate phosphatase 1
  • Vertebrate Orthologs
    12
  • Human Ortholog
    MINPP1, multiple inositol-polyphosphate phosphatase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HIPER1, MINPP2, MIPP
  • Links
    NCBI Gene ID: 9562
    neXtProt AC: NX_Q9UNW1
    UniProt: Q9UNW1

  • Chr Location
    10q23.2; chr10:87502792-87553461 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human MINPP1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Mice homozygous for a targeted null mutation exhibit no discernable phenotype; mice are viable and fertile with normal chondrocyte and bone development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 17330 NCBI Gene Model | MGI Sequence Detail 29602 C57BL/6J ±  kb
transcript NM_010799 RefSeq | MGI Sequence Detail 2619 C57BL/6  
polypeptide Q9Z2L6 UniProt | EBI | MGI Sequence Detail 481 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    Genomic 1
    cDNA 64
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2147435
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 3
  • Earliest
    J:54008 Chi H, et al., Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19. Genomics. 1999 Mar 15;56(3):324-36
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory