Sept7
Gene Detail

Symbol Name ID

Sept7 septin 7 MGI:1335094

Synonyms

Cdc10

Feature Type

protein coding gene

Genetic Map

Chromosome 9

10.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr9:25252439-25308571 bp, + strand From NCBI annotation of GRCm38   56133 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:1354  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: septin
Gene Tree: Sept7

Human homologs

Human Homolog		SEPT7, septin 7
NCBI Gene ID		989
neXtProt AC		NX_Q16181
Human Synonyms		CDC10, CDC3, NBLA02942, SEPT7A
Human Chr (Location)		7p14.2; chr7:35840596-35946715 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(23) : Targeted(1) Gene trapped(22)

Gene Ontology (GO) classifications

All GO classifications: (27 annotations)

Process	cell cycle, cell division, ...
Component	actin cytoskeleton, axon terminus, ...
Function	GTP binding, nucleotide binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (98)    Tissues (95)    Images (21)
Theiler Stages: 22, 23, 28

Assay Type	Results
RNA in situ	94
Western blot	4

cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(12) cDNA(10) Primer pair(2)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000001833 (Evidence)
Entrez Gene	235072 (Evidence)
DFCI	TC1573199, TC1591303, TC1621994
DoTS	DT.101197929, DT.101358737, DT.101723924, DT.55185810, DT.91390710, DT.94286438, DT.94286450
NIA Mouse Gene Index	U010177
Consensus CDS Project	CCDS40565.1
International Mouse Knockout Project Status	Sept7

Sequences

Length	Strain/Species
genomic	235072	NCBI Gene Model | MGI Sequence Detail	56133	C57BL/6J
transcript	NM_009859	RefSeq | MGI Sequence Detail	2533	C57BL/6
polypeptide	O55131	UniProt | EBI | MGI Sequence Detail	436	Not Applicable

All sequences(54) RefSeq(4) UniProt(8)

Polymorphisms

PCR(1) : SNPs(185 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000038	Cell division protein GTP binding
InterPro	IPR016491	Septin
InterPro	IPR008115	Septin 7
Protein Ontology	PR:000014659	septin-7

Graphical View of Protein Domain Structure

References

(Earliest) J:50856 Soulier S, et al., Sequence of murine CDC10 cDNA, gene organization and expression analysis. Biochim Biophys Acta. 1998 Nov 8;1442(2-3):339-46
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(36)