About   Help   FAQ
Slc22a2
Gene Detail
Symbol

Name
ID
Slc22a2
solute carrier family 22 (organic cation transporter), member 2
MGI:1335072
Synonyms
MGC:18339, Oct2, Orct2
Feature Type
protein coding gene
Genetic Map
Chromosome 17
8.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr17:12584189-12628465 bp, + strand
From Ensembl annotation of GRCm38

  44277 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68293  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc22a2

Human
homologs
Human Homolog SLC22A2, solute carrier family 22 (organic cation transporter), member 2
NCBI Gene ID 6582
neXtProt AC  NX_O15244
Human Synonyms  OCT2
Human Chr (Location)  6q25.3; chr6:160216762-160258931 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc22a2 interacts with 88 markers (Mir7-1, Mir29b-2, Mir92-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (9 records)
Data Summary: Results (208)    Tissues (151)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 192
Northern blot 2
RT-PCR 12
RNase protection 2
cDNA source data(27)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(38) Genomic(6) cDNA(27) Primer pair(5)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000040966 (Evidence)
Entrez Gene20518 (Evidence)
UniGene17322
DFCITC1583143, TC1596092
DoTSDT.483072, DT.91307542
Consensus CDS ProjectCCDS28392.1
International Mouse Knockout Project StatusSlc22a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040966 Ensembl Gene Model | MGI Sequence Detail 44277 C57BL/6J ±  kb
transcript ENSMUST00000046959 Ensembl | MGI Sequence Detail 2115 Not Applicable 
polypeptide ENSMUSP00000041186 Ensembl | MGI Sequence Detail 553 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms
All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(131 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005828 General substrate transporter
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
InterPro IPR004749 Organic cation transport protein
InterPro IPR005829 Sugar transporter, conserved site
Protein Ontology PR:000014988 solute carrier family 22 member 2
References
(Earliest) J:47780 Koehler MR, et al., The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26. Cytogenet Cell Genet. 1997;79(3-4):198-200
(Latest) J:198708 Sprowl JA, et al., Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11199-204
All references(45)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory