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Copa
Gene Detail
 Symbol
Name
ID
Copa
coatomer protein complex subunit alpha
MGI:1334462
Synonyms xenin
Feature Type protein coding gene
Genetic Map
Chromosome 1
79.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr1:172082529-172122330 bp, + strand
From VEGA annotation of GRCm38

  39802 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3218  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: coatomer, alpha subunit
Gene Tree: Copa

Human
homologs
Human Homolog COPA, coatomer protein complex, subunit alpha
NCBI Gene ID 1314
neXtProt AC  NX_P53621
Human Synonyms  HEP-COP
Human Chr (Location)  1q23.2; chr1:160288587-160343564 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Copa interacts with 255 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process intracellular protein transport, pancreatic juice secretion, ...
Component COPI vesicle coat, cytoplasm, ...
Function hormone activity, structural molecule activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (59)    Tissues (8)    Images (17)
Theiler Stages: 13, 15, 17, 23, 28
Assay TypeResults
RNA in situ 52
RT-PCR 7
cDNA source data(20)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(39) Genomic(16) cDNA(20) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000033968 (Evidence)
Ensembl Gene ModelENSMUSG00000026553 (Evidence)
Entrez Gene12847 (Evidence)
DFCITC1573938, TC1595276, TC1603029, TC1618681, TC1639460, TC1781569
DoTSDT.535775, DT.101136397, DT.101192136, DT.102558185, DT.110908252, DT.91335076, DT.91400067, DT.97361933
NIA Mouse Gene IndexU001100
Consensus CDS ProjectCCDS35780.1
International Mouse Knockout Project StatusCopa
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033968 VEGA Gene Model | MGI Sequence Detail 39802 C57BL/6J ±  kb
transcript OTTMUST00000085718 VEGA | MGI Sequence Detail 4351 Not Applicable 
polypeptide OTTMUSP00000046334 VEGA | MGI Sequence Detail 1233 Not Applicable 

For the selected sequences
All sequences(106) RefSeq(6) UniProt(11)
Polymorphisms PCR(1) : SNPs within 2kb(360 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016391 Coatomer alpha subunit
InterPro IPR010714 Coatomer, alpha subunit, C-terminal
InterPro IPR006692 Coatomer, WD associated region
InterPro IPR011048 Cytochrome cd1-nitrite reductase-like, C-terminal haem d1
InterPro IPR020472 G-protein beta WD-40 repeat
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000005733 coatomer subunit alpha
References (Earliest) J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
(Latest) J:191201 Todd AG, et al., COPI transport complexes bind to specific RNAs in neuronal cells. Hum Mol Genet. 2013 Feb 15;22(4):729-36
All references(38)
Other
accession IDs
MGI:2138485

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory