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Pex19
Gene Detail
 Symbol
Name
ID
Pex19
peroxisomal biogenesis factor 19
MGI:1334458
Synonyms peroxisome biogenesis factor 19, Pxf
Feature Type protein coding gene
Genetic Map
Chromosome 1
79.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr1:172126755-172136493 bp, + strand
From VEGA annotation of GRCm38

  9739 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:134253  Vertebrate Homology Class
1 human; 1 mouse; 3 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: peroxisomal biogenesis factor 19
Gene Tree: Pex19

Human
homologs
Human Homolog PEX19, peroxisomal biogenesis factor 19
NCBI Gene ID 5824
neXtProt AC  NX_P40855
Human Synonyms  D1S2223E, HK33, PBD12A, PMP1, PMPI, PXF, PXMP1
Human Chr (Location)  1q23.2; chr1:160276809-160285151 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PEX19
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(8)
Interactions
Pex19 interacts with 281 markers (Mir7b, Mir10a, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process chaperone-mediated protein folding, chaperone-mediated protein transport, ...
Component brush border membrane, cytoplasm, ...
Function ATPase binding, peroxisome membrane class-1 targeting sequence binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (17)    Tissues (6)   
Theiler Stages: 13, 15, 17, 28
Assay TypeResults
RNA in situ 10
RT-PCR 7
cDNA source data(149)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(171) Genomic(19) cDNA(150) Primer pair(2)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000029601 (Evidence)
Ensembl Gene ModelENSMUSG00000003464 (Evidence)
Entrez Gene19298 (Evidence)
UniGene247764
DFCITC1572293, TC1585750, TC1754352
DoTSDT.101401315, DT.110931414, DT.40143751, DT.532820
NIA Mouse Gene IndexU001101
Consensus CDS ProjectCCDS15508.1, CCDS48445.1
International Mouse Knockout Project StatusPex19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029601 VEGA Gene Model | MGI Sequence Detail 9739 C57BL/6J ±  kb
transcript OTTMUST00000073427 VEGA | MGI Sequence Detail 1917 Not Applicable 
polypeptide OTTMUSP00000037994 VEGA | MGI Sequence Detail 299 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(6) UniProt(2)
Polymorphisms PCR(1) : SNPs within 2kb(95 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006708 Pex19 protein
Protein Ontology PR:000012562 peroxisomal biogenesis factor 19
References (Earliest) J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
(Latest) J:184126 Kashiwayama Y, et al., 70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins. Exp Cell Res. 2009 Jan 15;315(2):190-205
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory