Pex19
Gene Detail

Symbol Name ID

Pex19 peroxisomal biogenesis factor 19 MGI:1334458

Synonyms

peroxisome biogenesis factor 19, Pxf

Feature Type

protein coding gene

Genetic Map

Chromosome 1

79.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)

Sequence Map

Chr1:172126755-172136493 bp, + strand From VEGA annotation of GRCm38   9739 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:37696  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: peroxisomal biogenesis factor 19
Gene Tree: Pex19

Human homologs

Human Homolog		PEX19, peroxisomal biogenesis factor 19
NCBI Gene ID		5824
neXtProt AC		NX_P40855
Human Synonyms		D1S2223E, HK33, PBD12A, PMP1, PMPI, PXF, PXMP1
Human Chr (Location)		1q23.2; chr1:160246599-160254941 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human PEX19

Alleles and phenotypes

All alleles(8) : Gene trapped(8)

Gene Ontology (GO) classifications

All GO classifications: (26 annotations)

Process	chaperone-mediated protein folding, chaperone-mediated protein transport, ...
Component	brush border membrane, cytoplasm, ...
Function	ATPase binding, peroxisome membrane class-1 targeting sequence binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (17)    Tissues (6)   
Theiler Stages: 13, 15, 17, 28

Assay Type	Results
RNA in situ	10
RT-PCR	7

cDNA source data(13)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(35) Genomic(19) cDNA(14) Primer pair(2)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000029601 (Evidence)
Ensembl Gene Model	ENSMUSG00000003464 (Evidence)
Entrez Gene	19298 (Evidence)
DFCI	TC1572293, TC1585750, TC1754352
DoTS	DT.101401315, DT.110931414, DT.40143751, DT.532820
NIA Mouse Gene Index	U001101
Consensus CDS Project	CCDS15508.1, CCDS48445.1
International Mouse Knockout Project Status	Pex19

Sequences

Length	Strain/Species
genomic	OTTMUSG00000029601	VEGA Gene Model | MGI Sequence Detail	9739	C57BL/6J
transcript	OTTMUST00000073427	VEGA | MGI Sequence Detail	1917	Not Applicable
polypeptide	OTTMUSP00000037994	VEGA | MGI Sequence Detail	299	Not Applicable

All sequences(59) RefSeq(4) UniProt(2)

Polymorphisms

PCR(1) : SNPs(58 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006708	Pex19 protein
Protein Ontology	PR:000012562	peroxisomal biogenesis factor 19

References

(Earliest) J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
(Latest) J:184126 Kashiwayama Y, et al., 70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins. Exp Cell Res. 2009 Jan 15;315(2):190-205
All references(35)