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Pex19 Gene Detail
Summary
  • Symbol
    Pex19
  • Name
    peroxisomal biogenesis factor 19
  • Synonyms
    peroxisome biogenesis factor 19, Pxf
  • Feature Type
    protein coding gene
  • IDs
    MGI:1334458
    NCBI Gene: 19298
  • Gene Overview
    MyGene.info: PEX19
Location & Maps
more
  • Sequence Map
    Chr1:172126755-172136493 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9739 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 79.54 cM
  • Mapping Data
    7 experiments
Homology
more
  • Human Ortholog
    PEX19, peroxisomal biogenesis factor 19
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PEX19, peroxisomal biogenesis factor 19
    Orthology source: HGNC, HomoloGene
  • Synonyms
    D1S2223E, HK33, PBD12A, PMP1, PMPI, PXF, PXMP1
  • Links
    NCBI Gene ID: 5824
    neXtProt AC: NX_P40855

  • Chr Location
    1q23.2; chr1:160276809-160285151 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human PEX19 associations

Human Disease Mouse Models
       Peroxisome Biogenesis Disorder 12a (zellweger); PBD12A   OMIM: 614886
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    2
  • Gene trapped
    8
  • Genomic Mutations
    2 involving Pex19
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029601 VEGA Gene Model | MGI Sequence Detail 9739 C57BL/6J ±  kb
transcript OTTMUST00000073427 VEGA | MGI Sequence Detail 1917 Not Applicable  
polypeptide OTTMUSP00000037994 VEGA | MGI Sequence Detail 299 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    94 from dbSNP Build 142
  • PCR
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000012562 peroxisomal biogenesis factor 19
  • InterPro Domains
    IPR006708 Pex19 protein
Molecular
Reagents
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  • All nucleic 171
    Genomic 19
    cDNA 150
    Primer pair 2

    Microarray probesets 7
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
  • Latest
    J:184126 Kashiwayama Y, et al., 70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins. Exp Cell Res. 2009 Jan 15;315(2):190-205

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory