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Cpne6 Gene Detail
Summary
  • Symbol
    Cpne6
  • Name
    copine VI
  • Synonyms
    neuronal copine
  • Feature Type
    protein coding gene
  • IDs
    MGI:1334445
    NCBI Gene: 12891
  • Gene Overview
    MyGene.info: CPNE6
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55510445-55517431 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 28.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1334445
protein coding gene Chr14:55510068-55517431 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021345
protein coding gene Chr14:49539355-49546339 (+)
A/J MGP_AJ_G0021304
protein coding gene Chr14:48555746-48562728 (+)
AKR/J MGP_AKRJ_G0021280
protein coding gene Chr14:50302481-50309463 (+)
BALB/cJ MGP_BALBcJ_G0021308
protein coding gene Chr14:48501068-48508078 (+)
C3H/HeJ MGP_C3HHeJ_G0021088
protein coding gene Chr14:49987346-49994332 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021746
protein coding gene Chr14:52030324-52037310 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019293
protein coding gene Chr14:46933050-46940151 (+)
CAST/EiJ MGP_CASTEiJ_G0020607
protein coding gene Chr14:46247060-46254054 (+)
CBA/J MGP_CBAJ_G0021055
protein coding gene Chr14:53589232-53596214 (+)
DBA/2J MGP_DBA2J_G0021176
protein coding gene Chr14:48275902-48282921 (+)
FVB/NJ MGP_FVBNJ_G0021158
protein coding gene Chr14:47731783-47739262 (+)
LP/J MGP_LPJ_G0021250
protein coding gene Chr14:50579054-50586058 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021182
protein coding gene Chr14:52951222-52958244 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021773
protein coding gene Chr14:49485949-49492933 (+)
PWK/PhJ MGP_PWKPhJ_G0020354
protein coding gene Chr14:44811221-44818321 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020182
protein coding gene Chr14:45478088-45485132 (+)
WSB/EiJ MGP_WSBEiJ_G0020660
protein coding gene Chr14:49767383-49774363 (+)



Homology
more
  • Human Ortholog
    CPNE6, copine 6
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CPNE6, copine 6
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 9362
    neXtProt AC: NX_O95741
    UniProt: O95741

  • Chr Location
    14q11.2; chr14:24070837-24078100 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022212 Ensembl Gene Model | MGI Sequence Detail 6987 C57BL/6J ±  kb
transcript ENSMUST00000074225 Ensembl | MGI Sequence Detail 2201 Not Applicable  
polypeptide ENSMUSP00000073847 Ensembl | MGI Sequence Detail 557 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145764, MGI:2145848
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:49331 Nakayama T, et al., N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression. FEBS Lett. 1998 May 22;428(1-2):80-4
  • Latest
    J:239922 Reinhard JR, et al., The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016 May 19;7:11613

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory