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Cd5l
Gene Detail
Symbol

Name
ID
Cd5l
CD5 antigen-like
MGI:1334419
Synonyms
AAC-11, AIM/Spalpha, Api6, Pdp 1/6, Sp-alpha
Feature Type
protein coding gene
Genetic Map
Chromosome 3
38.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr3:87357881-87371073 bp, + strand
From VEGA annotation of GRCm38

  13193 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55936  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

HCOP human homology predictions: CD5L
Gene Tree: Cd5l

Human
homologs
CD5L, CD5 molecule-like
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 922
neXtProt AC: NX_O43866

Human Synonyms: AIM, API6, PRO229, Spalpha, SP-ALPHA

Human Chr (Location): 1q23.1; chr1:157827071-157841844 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix )
 
Homozygous null mice exhibit enhanced and prolonged bacterial-induced granuloma formation and increased apoptosis of NKT and T cells.
 
Interactions
Cd5l interacts with 115 markers (Mir1b, Mir22, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process apoptotic process
Component blood microparticle, extracellular exosome, ...
Function scavenger receptor activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (81)    Tissues (33)    Images (37)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 65
Northern blot 16
cDNA source data(30)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(32) Genomic(1) cDNA(30) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000051776 (Evidence)
Ensembl Gene Model ENSMUSG00000015854 (Evidence)
Entrez Gene 11801 (Evidence)
UniGene 6676
DFCI TC1596716, TC1580870
DoTS DT.531182
NIA Mouse Gene Index U003398
Consensus CDS Project CCDS17451.1
International Mouse Phenotyping Consortium Status Cd5l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051776 VEGA Gene Model | MGI Sequence Detail 13193 C57BL/6J ±  kb
transcript OTTMUST00000130491 VEGA | MGI Sequence Detail 2036 Not Applicable 
polypeptide OTTMUSP00000069918 VEGA | MGI Sequence Detail 352 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(156 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001190 Speract/scavenger receptor
InterPro IPR017448 Speract/scavenger receptor-related
Protein Ontology PR:000005174 CD5 molecule-like
References
(Earliest) J:48250 Iwama A, et al., Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha. Nucleic Acids Res. 1998 Jun 15;26(12):3034-43
(Latest) J:218542 Maehara N, et al., Circulating AIM prevents hepatocellular carcinoma through complement activation. Cell Rep. 2014 Oct 9;9(1):61-74
All references(46)
Other
accession IDs
MGI:1333862, MGI:2139622

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory