Ppp1r17
Gene Detail

Symbol Name ID

Ppp1r17 protein phosphatase 1, regulatory subunit 17 MGI:1333876

Synonyms

Gsbs, G-substrate

Feature Type

protein coding gene

Genetic Map

Chromosome 6

27.65 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr6:56017515-56032688 bp, + strand From NCBI annotation of GRCm38   15174 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4849  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: G-substrate
Gene Tree: Ppp1r17

Human homologs

Human Homolog		PPP1R17, protein phosphatase 1, regulatory subunit 17
NCBI Gene ID		10842
neXtProt AC		NX_O96001
Human Synonyms		C7orf16, GSBS
Human Chr (Location)		7p15; chr7:31726631-31748069 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human PPP1R17

Alleles and phenotypes

All alleles(2) : Targeted(2)
 

Mice homozygous for a knock-out allele exhibit normal retina.

 

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	negative regulation of catalytic activity, regulation of phosphatase activity
Component	cytosol
Function	phosphatase inhibitor activity, protein phosphatase inhibitor activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (70)    Tissues (12)    Images (44)
Theiler Stages: 20, 21, 22, 23, 28

Assay Type	Results
RNA in situ	66
Northern blot	1
RT-PCR	3

cDNA source data(11)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(12) cDNA(11) Primer pair(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000002930 (Evidence)
Entrez Gene	19051 (Evidence)
UniGene	42096
DFCI	TC1584827
DoTS	DT.97354565
NIA Mouse Gene Index	U006911
Consensus CDS Project	CCDS20169.1
International Mouse Knockout Project Status	Ppp1r17

Sequences

Length	Strain/Species
genomic	19051	NCBI Gene Model | MGI Sequence Detail	15174	C57BL/6J
transcript	NM_011153	RefSeq | MGI Sequence Detail	1738	C57BL/6
polypeptide	Q9Z2E4	UniProt | EBI | MGI Sequence Detail	159	Not Applicable

All sequences(16) RefSeq(2) UniProt(2)

Polymorphisms

RFLP(1) : SNPs(102 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000008277	G-substrate

Graphical View of Protein Domain Structure

References

(Earliest) J:38063 Sowden JC, et al., The identification of novel sequences expressed in the mouse notochord. Mamm Genome. 1997 Jan;8(1):42-4
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)