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Cog1
Gene Detail
Symbol

Name
ID
Cog1
component of oligomeric golgi complex 1
MGI:1333873
Feature Type
protein coding gene
Genetic Map
Chromosome 11
79.10 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:113649169-113667054 bp, + strand
From VEGA annotation of GRCm38

  17886 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8411  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cog1

Human
homologs
Human Homolog COG1, component of oligomeric golgi complex 1
NCBI Gene ID 9382
neXtProt AC  NX_Q8WTW3
Human Synonyms  CDG2G, LDLB
Human Chr (Location)  17q25.1; chr17:73193034-73208507 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human COG1
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cog1 interacts with 87 markers (Mir18, Mir18b, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process protein transport, transport
Component Golgi apparatus, Golgi transport complex, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (18)    Tissues (2)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 18
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000003397 (Evidence)
Ensembl Gene ModelENSMUSG00000018661 (Evidence)
Entrez Gene16834 (Evidence)
Consensus CDS ProjectCCDS25599.1
International Mouse Knockout Project StatusCog1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003397 VEGA Gene Model | MGI Sequence Detail 17886 C57BL/6J ±  kb
transcript OTTMUST00000007130 VEGA | MGI Sequence Detail 3935 Not Applicable 
polypeptide OTTMUSP00000003398 VEGA | MGI Sequence Detail 980 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(13) UniProt(12)
Polymorphisms
SNPs within 2kb(190 from dbSNP Build 137)    SNPs within 2kb including multiple locations(194)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000005684 conserved oligomeric Golgi complex subunit 1
References
(Earliest) J:52531 Chatterton JE, et al., Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):915-20
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory