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Hsd17b10
Gene Detail
Symbol

Name
ID
Hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
MGI:1333871
Synonyms
Ads9, ERAB, Hadh2
Feature Type
protein coding gene
Genetic Map
Chromosome X
68.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:152001845-152004442 bp, + strand
From VEGA annotation of GRCm38

  2598 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68403  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: HSD17B10
Gene Tree: Hsd17b10

Human
homologs
HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 3028
neXtProt AC: NX_Q99714

Human Synonyms: 17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1

Human Chr (Location): Xp11.2; chrX:53431258-53434376 (-)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human HSD17B10

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Interactions
Hsd17b10 interacts with 36 markers (Mir17, Mir20b, Mir28b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(142)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase hsd17b10 ; ZFIN hsd17b10    NEW 
Molecular
reagents
All nucleic(142) cDNA(142)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000019648 (Evidence)
Ensembl Gene Model ENSMUSG00000025260 (Evidence)
Entrez Gene 15108 (Evidence)
UniGene 6994
DFCI TC1572702, TC1748931
DoTS DT.538023, DT.94170889
NIA Mouse Gene Index U020320
EC 1.1.1.178, 1.1.1.35, 1.1.1.51
Consensus CDS Project CCDS30471.1
International Mouse Phenotyping Consortium Status Hsd17b10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019648 VEGA Gene Model | MGI Sequence Detail 2598 C57BL/6J ±  kb
transcript OTTMUST00000046986 VEGA | MGI Sequence Detail 992 Not Applicable 
polypeptide OTTMUSP00000021232 VEGA | MGI Sequence Detail 271 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(5 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002347 Glucose/ribitol dehydrogenase
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR020904 Short-chain dehydrogenase/reductase, conserved site
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
Protein Ontology PR:000008774 3-hydroxyacyl-CoA dehydrogenase type-2
References
(Earliest) J:51470 Hansis C, et al., The gene for the Alzheimer-associated beta-amyloid-binding protein (ERAB) is differentially expressed in the testicular Leydig cells of the azoospermic by w/w(v) mouse. Eur J Biochem. 1998 Nov 15;258(1):53-60
(Latest) J:213151 Bogenhagen DF, et al., Initial steps in RNA processing and ribosome assembly occur at mitochondrial DNA nucleoids. Cell Metab. 2014 Apr 1;19(4):618-29
All references(41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory