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Hsd17b10
Gene Detail
 Symbol
Name
ID
Hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
MGI:1333871
Synonyms Ads9, ERAB, Hadh2
Feature Type protein coding gene
Genetic Map
Chromosome X
68.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:152001845-152004442 bp, + strand
From VEGA annotation of GRCm38

  2598 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68403  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Hsd17b10

Human
homologs
Human Homolog HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10
NCBI Gene ID 3028
neXtProt AC  NX_Q99714
Human Synonyms  17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1
Human Chr (Location)  Xp11.2; chrX:53431258-53434376 (-)  GRCh38
Disease Associations  (3) Diseases Associated with Human HSD17B10
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Interactions
Hsd17b10 interacts with 36 markers (Mir17, Mir20b, Mir28b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process metabolic process, oxidation-reduction process, ...
Component endoplasmic reticulum, mitochondrial inner membrane, ...
Function 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity, 3-hydroxyacyl-CoA dehydrogenase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (15)
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(142)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(142) cDNA(142)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000019648 (Evidence)
Ensembl Gene ModelENSMUSG00000025260 (Evidence)
Entrez Gene15108 (Evidence)
UniGene6994
DFCITC1572702, TC1748931
DoTSDT.538023, DT.94170889
NIA Mouse Gene IndexU020320
EC1.1.1.178, 1.1.1.35, 1.1.1.51
Consensus CDS ProjectCCDS30471.1
International Mouse Knockout Project StatusHsd17b10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019648 VEGA Gene Model | MGI Sequence Detail 2598 C57BL/6J ±  kb
transcript OTTMUST00000046986 VEGA | MGI Sequence Detail 992 Not Applicable 
polypeptide OTTMUSP00000021232 VEGA | MGI Sequence Detail 271 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(4)
Polymorphisms SNPs within 2kb(5 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002347 Glucose/ribitol dehydrogenase
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR020904 Short-chain dehydrogenase/reductase, conserved site
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
Protein Ontology PR:000008774 3-hydroxyacyl-CoA dehydrogenase type-2
References (Earliest) J:51470 Hansis C, et al., The gene for the Alzheimer-associated beta-amyloid-binding protein (ERAB) is differentially expressed in the testicular Leydig cells of the azoospermic by w/w(v) mouse. Eur J Biochem. 1998 Nov 15;258(1):53-60
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory