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Hsd17b10 Gene Detail
Summary
  • Symbol
    Hsd17b10
  • Name
    hydroxysteroid (17-beta) dehydrogenase 10
  • Synonyms
    Ads9, ERAB, Hadh2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333871
    NCBI Gene: 15108
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:150784892-150787438 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 68.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    113 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333871
 protein coding gene ChrX:150784841-150787438 (+)
129S1/SvImJ ENSMUSG00200031177
 protein coding gene ChrX:127590552-127593152 (+)
A/J ENSMUSG00195020496
 protein coding gene ChrX:132587903-132590478 (+)
AKR/J ENSMUSG00220031052
 protein coding gene ChrX:124598719-124601319 (+)
BALB/cJ ENSMUSG00180038025
 protein coding gene ChrX:127963676-127966248 (+)
C3H/HeJ ENSMUSG00175027670
 protein coding gene ChrX:132499209-132501807 (+)
C57BL/6NJ ENSMUSG00215020366
 protein coding gene ChrX:128264303-128266905 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033496
 protein coding gene ChrX:140640113-140642704 (+)
CAST/EiJ ENSTCUG00005032611
 protein coding gene ChrX:130285789-130288354 (+)
CBA/J ENSMUSG00210031354
 protein coding gene ChrX:129976526-129979125 (+)
DBA/2J ENSMUSG00185042354
 protein coding gene ChrX:144798009-144800608 (+)
FVB/NJ ENSMUSG00205016350
 protein coding gene ChrX:128545930-128548506 (+)
JF1/MsJ ENSUMUG00000038637
 protein coding gene ChrX:164996268-164998833 (+)
LP/J ENSMUSG00230031458
 protein coding gene ChrX:151599900-151602499 (+)
NOD/ShiLtJ ENSMUSG00190026019
 protein coding gene ChrX:129082190-129084767 (+)
NZO/HlLtJ ENSMUSG00225041898
 protein coding gene ChrX:155096906-155099505 (+)
PWK/PhJ ENSLUMG00010031810
 protein coding gene ChrX:126519998-126522569 (+)
SPRET/EiJ ENSMSPG00010036606
 protein coding gene ChrX:131383537-131386100 (+)
WSB/EiJ ENSIUOG00005037884
 protein coding gene ChrX:129553331-129555902 (+)



Homology
more
  • Human Ortholog
    HSD17B10, hydroxysteroid 17-beta dehydrogenase 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HSD17B10, hydroxysteroid 17-beta dehydrogenase 10
  • Synonyms
    17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, HSD10MD, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1
  • Links
    NCBI Gene ID: 3028
    UniProt: Q99714

  • Chr Location
    Xp11.22; chrX:53431258-53434376 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human HSD17B10 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    95
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    691
  • Tissues
    94
  • cDNA Data
    143
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 15108 NCBI Gene Model | MGI Sequence Detail 2547 C57BL/6J ±  kb
transcript NM_016763 RefSeq | MGI Sequence Detail 938 C57BL/6  
polypeptide O08756 UniProt | EBI | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 143
    cDNA 143

    Microarray probesets 6
References
more
  • Summaries
    All 52
    Developmental Gene Expression 2
    Gene Ontology 15
    Phenotypes 4
  • Earliest
    J:49241 Sambamurti K, et al., ERAB contains a putative noncleavable signal peptide. Biochem Biophys Res Commun. 1998 Aug 19;249(2):546-9
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory