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Tnnt1
Gene Detail
 Symbol
Name
ID
Tnnt1
troponin T1, skeletal, slow
MGI:1333868
Synonyms skeletal muscle slow-twitch TnT, ssTnT, sTnT, Tnt
Feature Type protein coding gene
Genetic Map
Chromosome 7
2.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr7:4504570-4516382 bp, - strand
From VEGA annotation of GRCm38

  11813 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20704  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Tnnt1

Human
homologs
Human Homolog TNNT1, troponin T type 1 (skeletal, slow)
NCBI Gene ID 7138
neXtProt AC  NX_P13805
Human Synonyms  ANM, NEM5, STNT, TNT, TNTS
Human Chr (Location)  19q13.4; chr19:55132793-55149332 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human TNNT1
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tnnt1 interacts with 14 markers (Mir207, Mir326, Mir367, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process negative regulation of muscle contraction, regulation of muscle contraction, ...
Component troponin complex
Function tropomyosin binding, troponin T binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (24)    Tissues (11)    Images (3)
Theiler Stages: 15, 17, 20, 21, 22, 23, 24, 26, 27, 28
Assay TypeResults
RT-PCR 24
cDNA source data(24)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(32) Genomic(5) cDNA(24) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000036009 (Evidence)
Ensembl Gene ModelENSMUSG00000064179 (Evidence)
Entrez Gene21955 (Evidence)
UniGene358643
DFCITC1585218, TC1595826, TC1642387, TC1701895
DoTSDT.87068663, DT.94396255, DT.94396257, DT.94396260
NIA Mouse Gene IndexU028085
Consensus CDS ProjectCCDS51973.1, CCDS71879.1, CCDS71880.1
International Mouse Knockout Project StatusTnnt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036009 VEGA Gene Model | MGI Sequence Detail 11813 C57BL/6J ±  kb
transcript OTTMUST00000092406 VEGA | MGI Sequence Detail 1059 Not Applicable 
polypeptide OTTMUSP00000051064 VEGA | MGI Sequence Detail 262 Not Applicable 

For the selected sequences
All sequences(103) RefSeq(20) UniProt(11)
Polymorphisms SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001978 Troponin
Protein Ontology PR:000016508 troponin T, slow skeletal muscle
References (Earliest) J:39609 Koch A, et al., cDNA cloning and chromosomal mapping of mouse fast skeletal muscle troponin T. Mamm Genome. 1997 May;8(5):346-8
(Latest) J:207861 Manthey AL, et al., Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110
All references(53)
Other
accession IDs
MGI:2142213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory