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Klf9 Gene Detail
Summary
  • Symbol
    Klf9
  • Name
    Kruppel-like factor 9
  • Synonyms
    2310051E17Rik, Bteb1, BTEB-1, Klf9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333856
    NCBI Gene: 16601
  • Gene Overview
    MyGene.info: KLF9
Location & Maps
more
  • Sequence Map
    Chr19:23141226-23166911 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      25686 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 17.90 cM, cytoband C1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    KLF9, Kruppel like factor 9
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KLF9, Kruppel like factor 9
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BTEB, BTEB1
  • Links
    NCBI Gene ID: 687
    neXtProt AC: NX_Q13886

  • Chr Location
    9q13; chr9:70384597-70414657 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 931
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 chicken;1 frog, western clawed
  • HCOP
    human homology predictions: KLF9
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    31 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutant mice display only mild neurological defects evident by impaired performance in rotarod and contextual fear-conditioning tests.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 16601 NCBI Gene Model | MGI Sequence Detail 25686 C57BL/6J ±  kb
transcript NM_010638 RefSeq | MGI Sequence Detail 3263 C57BL/6  
polypeptide O35739 UniProt | EBI | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    308 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000009369 krueppel-like factor 9
  • InterPro Domains
    IPR007087 Zinc finger, C2H2
    IPR015880 Zinc finger, C2H2-like
    IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Molecular
Reagents
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  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
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MGI:1917523, MGI:2147456
References
more
  • Summaries
    All 72
    Developmental Gene Expression 11
    Gene Ontology 6
    Phenotypes 31
  • Earliest
    J:51610 Imhof A, et al., Transcriptional regulation of the AP-2alpha promoter by BTEB-1 and AP-2rep, a novel wt-1/ egr-related zinc finger repressor. Mol Cell Biol. 1999 Jan;19(1):194-204
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory