About   Help   FAQ
Klf9
Gene Detail
Symbol

Name
ID
Klf9
Kruppel-like factor 9
MGI:1333856
Synonyms
2310051E17Rik, Bteb1, BTEB-1, Klf9
Feature Type
protein coding gene
Genetic Map
Chromosome 19
17.90 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:23141226-23166911 bp, + strand
From NCBI annotation of GRCm38

  25686 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:931  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog

Gene Tree: Klf9

Human
homologs
Human Homolog KLF9, Kruppel-like factor 9
NCBI Gene ID 687
neXtProt AC  NX_Q13886
Human Synonyms  BTEB, BTEB1
Human Chr (Location)  9q13; chr9:70384597-70414657 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(345) : Gene trapped(343) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice display only mild neurological defects evident by impaired performance in rotarod and contextual fear-conditioning tests.
 
Interactions
Klf9 interacts with 288 markers (Mir7-1, Mir10a, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cellular response to thyroid hormone stimulus, embryo implantation, ...
Component cytoplasm, nucleus, ...
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (174)    Tissues (89)    Images (37)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 166
RT-PCR 8
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(14) Primer pair(1)
Microarray probesets(10)
Other database
links
Ensembl Gene ModelENSMUSG00000033863 (Evidence)
Entrez Gene16601 (Evidence)
DFCITC1575034, TC1600184, TC1672211
DoTSDT.531049, DT.87025964, DT.94142605, DT.94333378
NIA Mouse Gene IndexU043714, U306051
Consensus CDS ProjectCCDS29706.1
International Mouse Knockout Project StatusKlf9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16601 NCBI Gene Model | MGI Sequence Detail 25686 C57BL/6J ±  kb
transcript NM_010638 RefSeq | MGI Sequence Detail 3263 C57BL/6 
polypeptide O35739 UniProt | EBI | MGI Sequence Detail 244 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(310 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000009369 krueppel-like factor 9
Graphical View of Protein Domain Structure
References
(Earliest) J:51610 Imhof A, et al., Transcriptional regulation of the AP-2alpha promoter by BTEB-1 and AP-2rep, a novel wt-1/ egr-related zinc finger repressor. Mol Cell Biol. 1999 Jan;19(1):194-204
(Latest) J:212498 Zucker SN, et al., Nrf2 amplifies oxidative stress via induction of Klf9. Mol Cell. 2014 Mar 20;53(6):916-28
All references(70)
Other
accession IDs
MGI:1917523, MGI:2147456

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory