Klf9
Gene Detail

Symbol Name ID

Klf9 Kruppel-like factor 9 MGI:1333856

Synonyms

2310051E17Rik, Bteb1, BTEB-1, Klf9

Feature Type

protein coding gene

Genetic Map

Chromosome 19

17.90 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr19:23141226-23166911 bp, + strand From NCBI annotation of GRCm38   25686 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:931  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken

Gene Tree: Klf9

Human homologs

Human Homolog		KLF9, Kruppel-like factor 9
NCBI Gene ID		687
neXtProt AC		NX_Q13886
Human Synonyms		BTEB, BTEB1
Human Chr (Location)		9q13; chr9:72999513-73029573 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(345) : Targeted(2) Gene trapped(343)
 

Homozygous mutant mice display only mild neurological defects evident by impaired performance in rotarod and contextual fear-conditioning tests.

 

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	cellular response to thyroid hormone stimulus, embryo implantation, ...
Component	nucleus
Function	DNA binding, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (9 records)
Data Summary: Results (181)    Tissues (94)    Images (37)
Theiler Stages: 2, 3, 4, 5, 12, 17, 18, 21, 22, 23, 24, 28

Assay Type	Results
RNA in situ	166
RT-PCR	15

cDNA source data(13)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(15) cDNA(14) Primer pair(1)
Microarray probesets(10)

Other database links

Ensembl Gene Model	ENSMUSG00000033863 (Evidence)
Entrez Gene	16601 (Evidence)
DFCI	TC1575034, TC1600184, TC1672211
DoTS	DT.531049, DT.87025964, DT.94142605, DT.94333378
NIA Mouse Gene Index	U043714, U306051
Consensus CDS Project	CCDS29706.1
International Mouse Knockout Project Status	Klf9

Sequences

Length	Strain/Species
genomic	16601	NCBI Gene Model | MGI Sequence Detail	25686	C57BL/6J
transcript	NM_010638	RefSeq | MGI Sequence Detail	3263	C57BL/6
polypeptide	O35739	UniProt | EBI | MGI Sequence Detail	244	Not Applicable

All sequences(35) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(115 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007087	Zinc finger, C2H2
InterPro	IPR015880	Zinc finger, C2H2-like
InterPro	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology	PR:000009369	krueppel-like factor 9

Graphical View of Protein Domain Structure

References

(Earliest) J:51610 Imhof A, et al., Transcriptional regulation of the AP-2alpha promoter by BTEB-1 and AP-2rep, a novel wt-1/ egr-related zinc finger repressor. Mol Cell Biol. 1999 Jan;19(1):194-204
(Latest) J:191800 Bagamasbad P, et al., Molecular basis for glucocorticoid induction of the Kruppel-like factor 9 gene in hippocampal neurons. Endocrinology. 2012 Nov;153(11):5334-45
All references(63)

Other accession IDs

MGI:1917523, MGI:2147456