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Hs3st3b1 Gene Detail
Summary
  • Symbol
    Hs3st3b1
  • Name
    heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
  • Synonyms
    3Ost3b, 3-OST-3B, 3OST3B1, HS3ST3B1, m3-OST-3B
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333853
    NCBI Gene: 54710
  • Gene Overview
    MyGene.info: HS3ST3B1
Location & Maps
more
  • Sequence Map
    Chr11:63885792-63922290 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      36499 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 39.47 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    HS3ST3B1, heparan sulfate-glucosamine 3-sulfotransferase 3B1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HS3ST3B1, heparan sulfate-glucosamine 3-sulfotransferase 3B1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    3-OST-3B, 3OST3B1, h3-OST-3B
  • Links
    NCBI Gene ID: 9953
    neXtProt AC: NX_Q9Y662

  • Chr Location
    17p12; chr17:14301050-14349406 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Hs3st3b1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007900 VEGA Gene Model | MGI Sequence Detail 36499 C57BL/6J ±  kb
transcript OTTMUST00000017960 VEGA | MGI Sequence Detail 4911 Not Applicable  
polypeptide OTTMUSP00000008256 VEGA | MGI Sequence Detail 390 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    282 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008760 heparan sulfate glucosamine 3-O-sulfotransferase 3A1
  • EC
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR000863 Sulfotransferase domain
Molecular
Reagents
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  • All nucleic 21
    cDNA 18
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
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MGI:2144429, MGI:2144549
References
more
  • Summaries
    All 32
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:53037 Shworak NW, et al., Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci. J Biol Chem. 1999 Feb 19;274(8):5170-84
  • Latest
    J:213873 Chen Z, et al., FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands. Development. 2014 Jul;141(13):2691-701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory