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Magea4 Gene Detail
Summary
  • Symbol
    Magea4
  • Name
    melanoma antigen, family A, 4
  • Synonyms
    Mage-a4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333839
    NCBI Gene: 17140
  • Gene Overview
    MyGene.info: MAGEA11
  • Alliance
Location &
Maps
more
  • Sequence Map
    ChrX:72222017-72222964 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.20 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333839
protein coding gene ChrX:72221015-72222964 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035790
protein coding gene ChrX:67887274-67888221 (+)
A/J MGP_AJ_G0035774
protein coding gene ChrX:68130024-68130971 (+)
AKR/J MGP_AKRJ_G0035696
protein coding gene ChrX:69963536-69964483 (+)
BALB/cJ MGP_BALBcJ_G0035761
protein coding gene ChrX:67155968-67156915 (+)
C3H/HeJ MGP_C3HHeJ_G0035464
protein coding gene ChrX:68406102-68407049 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036291
protein coding gene ChrX:69963578-69964525 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033138
protein coding gene ChrX:67326065-67327177 (+)
CAST/EiJ MGP_CASTEiJ_G0034756
protein coding gene ChrX:53778396-53779752 (+)
CBA/J MGP_CBAJ_G0035439
protein coding gene ChrX:71893411-71894358 (+)
DBA/2J MGP_DBA2J_G0035592
protein coding gene ChrX:67593060-67594007 (+)
FVB/NJ MGP_FVBNJ_G0035543
protein coding gene ChrX:66952118-66953065 (+)
LP/J MGP_LPJ_G0035681
protein coding gene ChrX:68736499-68737446 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035578
protein coding gene ChrX:74470177-74471124 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036312
protein coding gene ChrX:67751554-67752501 (+)
PWK/PhJ MGP_PWKPhJ_G0034456
protein coding gene ChrX:51787762-51788709 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034291
protein coding gene ChrX:54681538-54682485 (+)
WSB/EiJ MGP_WSBEiJ_G0034898
protein coding gene ChrX:67072662-67073609 (+)



Homology
more
  • Human Ortholog
    MAGEA11, MAGE family member A11
  • Vertebrate Orthologs
    5
  • Human Ortholog
    MAGEA11, MAGE family member A11
    Orthology source: HomoloGene
  • Synonyms
    CT1.11, MAGE11, MAGE-11, MAGEA-11
  • Links
    NCBI Gene ID: 4110
    neXtProt AC: NX_P43364
    UniProt: P43364

  • Chr Location
    Xq28; chrX:149688202-149717268 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033343 Ensembl Gene Model | MGI Sequence Detail 948 C57BL/6J ±  kb
transcript ENSMUST00000048675 Ensembl | MGI Sequence Detail 948 Not Applicable  
polypeptide ENSMUSP00000046715 Ensembl | MGI Sequence Detail 315 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR037445 Melanoma-associated antigen
    IPR021072 Melanoma associated antigen, N-terminal
Molecular
Reagents
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  • All nucleic 6
    cDNA 4
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 9
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:52871 De Plaen E, et al., A new family of mouse genes homologous to the human MAGE genes. Genomics. 1999 Jan 15;55(2):176-84
  • Latest
    J:256265 Gordeeva OF, et al., Expression of Cancer-Testis Antigens of the Mage Family in Mouse Oocytes and Early Embryos. Russian Journal of Developmental Biology. 2017;48(4):287-294

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory