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Magea6 Gene Detail
Summary
  • Symbol
    Magea6
  • Name
    MAGE family member A6
  • Synonyms
    Mage-a6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333837
    NCBI Gene: 17142
  • Alliance
Location &
Maps
more
  • Sequence Map
    ChrX:153707008-153718983 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 72.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333837
protein coding gene ChrX:153706891-153719070 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036208
protein coding gene ChrX:152964553-152970406 (-)
A/J MGP_AJ_G0036180
protein coding gene ChrX:152181493-152248964 (-)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0035879
protein coding gene ChrX:153102884-153105117 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0035854
protein coding gene ChrX:161736989-161740172 (-)
DBA/2J MGP_DBA2J_G0036015
protein coding gene ChrX:151043886-151044559 (-)
FVB/NJ MGP_FVBNJ_G0035950
protein coding gene ChrX:150297458-150352110 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MAGEA10, MAGE family member A10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGEA10, MAGE family member A10
  • Synonyms
    CT1.10, MAGE10
  • Links
    NCBI Gene ID: 4109
    neXtProt AC: NX_P43363
    UniProt: P43363

  • Chr Location
    Xq28; chrX:152133310-152138578 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063728 Ensembl Gene Model | MGI Sequence Detail 11976 C57BL/6J ±  kb
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
Molecular
Reagents
less
  • All nucleic 6
    cDNA 4
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 10
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:52871 De Plaen E, et al., A new family of mouse genes homologous to the human MAGE genes. Genomics. 1999 Jan 15;55(2):176-84
  • Latest
    J:310310 Gordeeva O, et al., Expression dynamics of Mage family genes during self-renewal and differentiation of mouse pluripotent stem and teratocarcinoma cells. Oncotarget. 2019 May 14;10(35):3248-3266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory