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Hs3st2 Gene Detail
Summary
  • Symbol
    Hs3st2
  • Name
    heparan sulfate (glucosamine) 3-O-sulfotransferase 2
  • Synonyms
    6430516N12Rik, A830061E14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333802
    NCBI Gene: 195646
  • Gene Overview
    MyGene.info: HS3ST2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:121391859-121501770 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 65.07 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    816 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333802
protein coding gene Chr7:121391610-121501770 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032942
protein coding gene Chr7:125431730-125535438 (+)
A/J MGP_AJ_G0032925
protein coding gene Chr7:122170337-122281618 (+)
AKR/J MGP_AKRJ_G0032857
protein coding gene Chr7:125285183-125394467 (+)
BALB/cJ MGP_BALBcJ_G0032930
protein coding gene Chr7:121872839-121981149 (+)
C3H/HeJ MGP_C3HHeJ_G0032640
protein coding gene Chr7:125202149-125315753 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033436
protein coding gene Chr7:130377301-130486125 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030408
protein coding gene Chr7:123519842-123624333 (+)
CAST/EiJ MGP_CASTEiJ_G0031968
protein coding gene Chr7:116983788-117097024 (+)
CBA/J MGP_CBAJ_G0032613
protein coding gene Chr7:134730476-134851671 (+)
DBA/2J MGP_DBA2J_G0032765
protein coding gene Chr7:120194441-120301839 (+)
FVB/NJ MGP_FVBNJ_G0032718
protein coding gene Chr7:120038917-120148645 (+)
LP/J MGP_LPJ_G0032859
protein coding gene Chr7:126881178-126988176 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032750
protein coding gene Chr7:136182442-136292182 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033456
protein coding gene Chr7:124286052-124397510 (+)
PWK/PhJ MGP_PWKPhJ_G0031676
protein coding gene Chr7:113114079-113222545 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031522
protein coding gene Chr7:111056454-111164859 (+)
WSB/EiJ MGP_WSBEiJ_G0032081
protein coding gene Chr7:125209933-125315006 (+)



Homology
more
  • Human Ortholog
    HS3ST2, heparan sulfate-glucosamine 3-sulfotransferase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    HS3ST2, heparan sulfate-glucosamine 3-sulfotransferase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    30ST2, 3OST2
  • Links
    NCBI Gene ID: 9956
    neXtProt AC: NX_Q9Y278
    UniProt: Q9Y278

  • Chr Location
    16p12.2; chr16:22814162-22916338 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 21220
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: HS3ST2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Mice homozygous for a targeted allele exhibit no abnormal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046321 Ensembl Gene Model | MGI Sequence Detail 109912 C57BL/6J ±  kb
transcript ENSMUST00000084628 Ensembl | MGI Sequence Detail 2278 Not Applicable  
polypeptide ENSMUSP00000081678 Ensembl | MGI Sequence Detail 367 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 12
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142237, MGI:3045366
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:53037 Shworak NW, et al., Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci. J Biol Chem. 1999 Feb 19;274(8):5170-84
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory