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Hs3st2 Gene Detail
Summary
  • Symbol
    Hs3st2
  • Name
    heparan sulfate (glucosamine) 3-O-sulfotransferase 2
  • Synonyms
    6430516N12Rik, A830061E14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333802
    NCBI Gene: 195646
  • Gene Overview
    MyGene.info: HS3ST2
Location & Maps
more
  • Sequence Map
    Chr7:121391859-121501770 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      109912 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 65.07 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    HS3ST2, heparan sulfate-glucosamine 3-sulfotransferase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    HS3ST2, heparan sulfate-glucosamine 3-sulfotransferase 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    30ST2, 3OST2
  • Links
    NCBI Gene ID: 9956
    neXtProt AC: NX_Q9Y278

  • Chr Location
    16p12; chr16:22814203-22916338 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Mice homozygous for a targeted allele exhibit no abnormal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000058095 VEGA Gene Model | MGI Sequence Detail 109912 C57BL/6J ±  kb
transcript OTTMUST00000142651 VEGA | MGI Sequence Detail 2278 Not Applicable  
polypeptide OTTMUSP00000074405 VEGA | MGI Sequence Detail 367 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    816 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000008759 heparan sulfate glucosamine 3-O-sulfotransferase 2
  • EC
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR000863 Sulfotransferase domain
Molecular
Reagents
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  • All nucleic 14
    cDNA 10
    Primer pair 2
    Other 2

    Microarray probesets 5
Other
Accession IDs
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MGI:2142237, MGI:3045366
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:53037 Shworak NW, et al., Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci. J Biol Chem. 1999 Feb 19;274(8):5170-84
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory