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Klf12
Gene Detail
 Symbol
Name
ID
Klf12
Kruppel-like factor 12
MGI:1333796
Synonyms 2700063E05Rik, AP-2rep, B130052C06Rik, D530033K05Rik
Feature Type protein coding gene
Genetic Map
Chromosome 14
50.90 cM, cytoband E2.2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr14:99874486-100149764 bp, - strand
From Ensembl annotation of GRCm38

  275279 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21417  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Klf12

Human
homologs
Human Homolog KLF12, Kruppel-like factor 12
NCBI Gene ID 11278
neXtProt AC  NX_Q9Y4X4
Human Synonyms  AP-2rep, AP2REP
Human Chr (Location)  13q22; chr13:73686012-74134263 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(49) : Gene trapped(48) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klf12 interacts with 240 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, ...
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (63)    Tissues (63)    Images (5)
Theiler Stages: 2, 3, 4, 5, 15, 17, 19, 21, 23, 28
Assay TypeResults
RNA in situ 55
RT-PCR 8
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(14) Primer pair(1)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000072294 (Evidence)
Entrez Gene16597 (Evidence)
DFCITC1588929, TC1609378, TC1633664, TC1635422
DoTSDT.40176451, DT.94221359, DT.97384041
NIA Mouse Gene IndexU035864, U035866
Consensus CDS ProjectCCDS36998.1
International Mouse Knockout Project StatusKlf12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000072294 Ensembl Gene Model | MGI Sequence Detail 275279 C57BL/6J ±  kb
transcript ENSMUST00000097079 Ensembl | MGI Sequence Detail 1856 Not Applicable 
polypeptide ENSMUSP00000094844 Ensembl | MGI Sequence Detail 402 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(1755 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000009356 krueppel-like factor 12
References (Earliest) J:51610 Imhof A, et al., Transcriptional regulation of the AP-2alpha promoter by BTEB-1 and AP-2rep, a novel wt-1/ egr-related zinc finger repressor. Mol Cell Biol. 1999 Jan;19(1):194-204
(Latest) J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39
All references(48)
Other
accession IDs
MGI:1353650, MGI:1919848, MGI:1925972, MGI:2145611

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory