About   Help   FAQ
Klf12
Gene Detail
Symbol

Name
ID
Klf12
Kruppel-like factor 12
MGI:1333796
Synonyms
2700063E05Rik, AP-2rep, B130052C06Rik, D530033K05Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
50.90 cM, cytoband E2.2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr14:99874486-100149764 bp, - strand
From Ensembl annotation of GRCm38

  275279 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21417  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Klf12

Human
homologs
Human Homolog KLF12, Kruppel-like factor 12
NCBI Gene ID 11278
neXtProt AC  NX_Q9Y4X4
Human Synonyms  AP-2rep, AP2REP
Human Chr (Location)  13q22; chr13:73686012-74134263 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(49) : Gene trapped(48) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klf12 interacts with 240 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (63)    Tissues (63)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 55
RT-PCR 8
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(14) Primer pair(1)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000072294 (Evidence)
Entrez Gene16597 (Evidence)
DFCITC1588929, TC1635422, TC1633664, TC1609378
DoTSDT.94221359, DT.40176451, DT.97384041
NIA Mouse Gene IndexU035866, U035864
Consensus CDS ProjectCCDS36998.1
International Mouse Knockout Project StatusKlf12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000072294 Ensembl Gene Model | MGI Sequence Detail 275279 C57BL/6J ±  kb
transcript ENSMUST00000097079 Ensembl | MGI Sequence Detail 1856 Not Applicable 
polypeptide ENSMUSP00000094844 Ensembl | MGI Sequence Detail 402 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(10) UniProt(1)
Polymorphisms
SNPs within 2kb(1755 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000009356 krueppel-like factor 12
References
(Earliest) J:51610 Imhof A, et al., Transcriptional regulation of the AP-2alpha promoter by BTEB-1 and AP-2rep, a novel wt-1/ egr-related zinc finger repressor. Mol Cell Biol. 1999 Jan;19(1):194-204
(Latest) J:210983 Chang AC, et al., A Notch-dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion. Dev Dyn. 2014 Jul;243(7):894-905
All references(49)
Other
accession IDs
MGI:1353650, MGI:1919848, MGI:1925972, MGI:2145611

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory