About   Help   FAQ
Srp72
Gene Detail
Symbol

Name
ID
Srp72
signal recognition particle 72
MGI:1333795
Synonyms
5730576P14Rik, 72kDa
Feature Type
protein coding gene
Genetic Map
Chromosome 5
41.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:76974683-76999937 bp, + strand
From VEGA annotation of GRCm38

  25255 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38254  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SRP72
Protein SuperFamily: SRP72
Gene Tree: Srp72

Human
homologs
SRP72, signal recognition particle 72kDa
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 6731
neXtProt AC: NX_O76094

Human Synonyms: BMFF, BMFS1, HEL103

Human Chr (Location): 4q11; chr4:56467596-56503681 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SRP72

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(6) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Srp72 interacts with 278 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase srp72    NEW 
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000026549 (Evidence)
Ensembl Gene Model ENSMUSG00000036323 (Evidence)
Entrez Gene 66661 (Evidence)
DFCI TC1598056, TC1598516
DoTS DT.101386135, DT.99859032, DT.101339674, DT.94342765, DT.495386, DT.103570594
NIA Mouse Gene Index U005716
Consensus CDS Project CCDS39119.1
International Mouse Phenotyping Consortium Status Srp72
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026549 VEGA Gene Model | MGI Sequence Detail 25255 C57BL/6J ±  kb
transcript OTTMUST00000065682 VEGA | MGI Sequence Detail 3625 Not Applicable 
polypeptide OTTMUSP00000032768 VEGA | MGI Sequence Detail 671 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(2) UniProt(7)
Polymorphisms
SNPs within 2kb(123 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026270 Signal recognition particle, SRP72 subunit
InterPro IPR013699 Signal recognition particle, SRP72 subunit, RNA-binding
InterPro IPR011990 Tetratricopeptide-like helical
InterPro IPR019734 Tetratricopeptide repeat
InterPro IPR013026 Tetratricopeptide repeat-containing domain
Protein Ontology PR:000015627 signal recognition particle subunit SRP72
References
(Earliest) J:51619 Utz PJ, et al., The 72-kDa component of signal recognition particle is cleaved during apoptosis. J Biol Chem. 1998 Dec 25;273(52):35362-70
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:1913911, MGI:2140810, MGI:2141290, MGI:3039569

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory