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Srp72 Gene Detail
Summary
  • Symbol
    Srp72
  • Name
    signal recognition particle 72
  • Synonyms
    5730576P14Rik, 72kDa
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333795
    NCBI Gene: 66661
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:76974701-76999935 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 41.45 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333795
protein coding gene Chr5:76974683-76999937 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029651
protein coding gene Chr5:77188367-77216704 (+)
A/J MGP_AJ_G0029619
protein coding gene Chr5:74237961-74263185 (+)
AKR/J MGP_AKRJ_G0029567
protein coding gene Chr5:76660891-76686864 (+)
BALB/cJ MGP_BALBcJ_G0029628
protein coding gene Chr5:74972946-74999433 (+)
C3H/HeJ MGP_C3HHeJ_G0029351
protein coding gene Chr5:77033237-77060437 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030082
protein coding gene Chr5:80275994-80305836 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027323
protein coding gene Chr5:69868102-69893347 (+)
CAST/EiJ MGP_CASTEiJ_G0028759
protein coding gene Chr5:76238871-76268865 (+)
CBA/J MGP_CBAJ_G0029320
protein coding gene Chr5:82915771-82950664 (+)
DBA/2J MGP_DBA2J_G0029465
protein coding gene Chr5:74298815-74324657 (+)
FVB/NJ MGP_FVBNJ_G0029426
protein coding gene Chr5:73496540-73522239 (+)
LP/J MGP_LPJ_G0029552
protein coding gene Chr5:77625624-77652835 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029454
protein coding gene Chr5:86056056-86081363 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030115
protein coding gene Chr5:76210879-76237510 (+)
PWK/PhJ MGP_PWKPhJ_G0028482
protein coding gene Chr5:73314817-73340430 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028317
protein coding gene Chr5:75565810-75594359 (+)
WSB/EiJ MGP_WSBEiJ_G0028839
protein coding gene Chr5:76539233-76569412 (+)



Homology
more
  • Human Ortholog
    SRP72, signal recognition particle 72
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SRP72, signal recognition particle 72
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BMFF, BMFS1, HEL103
  • Links
    NCBI Gene ID: 6731
    neXtProt AC: NX_O76094
    UniProt: O76094

  • Chr Location
    4q12; chr4:56466877-56503681 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 38254
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SRP72
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66661 NCBI Gene Model | MGI Sequence Detail 25235 C57BL/6J ±  kb
transcript NM_025691 RefSeq | MGI Sequence Detail 3605 C57BL/6  
polypeptide NP_079967 RefSeq | MGI Sequence Detail 671 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • InterPro Domains
    IPR031545 Putative TPR-like repeat
    IPR026270 Signal recognition particle, SRP72 subunit
    IPR013699 Signal recognition particle, SRP72 subunit, RNA-binding
    IPR011990 Tetratricopeptide-like helical domain superfamily
    IPR019734 Tetratricopeptide repeat
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 6
Other
Accession IDs
less
MGI:1913911, MGI:2140810, MGI:2141290, MGI:3039569
References
more
  • Summaries
    All 35
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory