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Srp72
Gene Detail
 Symbol
Name
ID
Srp72
signal recognition particle 72
MGI:1333795
Synonyms 5730576P14Rik, 72kDa
Feature Type protein coding gene
Genetic Map
Chromosome 5
41.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:76974683-76999937 bp, + strand
From VEGA annotation of GRCm38

  25255 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38254  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: SRP72
Gene Tree: Srp72

Human
homologs
Human Homolog SRP72, signal recognition particle 72kDa
NCBI Gene ID 6731
neXtProt AC  NX_O76094
Human Synonyms  BMFF, HEL103
Human Chr (Location)  4q11; chr4:56467204-56503681 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SRP72
Alleles
and
phenotypes
All alleles(8) : Targeted(2) Gene trapped(6)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process response to drug, SRP-dependent cotranslational protein targeting to membrane
Component cytoplasm, endoplasmic reticulum, ...
Function poly(A) RNA binding, signal recognition particle binding
External Resources: FuncBase
Expression
cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000026549 (Evidence)
Ensembl Gene ModelENSMUSG00000036323 (Evidence)
Entrez Gene66661 (Evidence)
DFCITC1598056, TC1598516
DoTSDT.101339674, DT.101386135, DT.103570594, DT.495386, DT.94342765, DT.99859032
NIA Mouse Gene IndexU005716
Consensus CDS ProjectCCDS39119.1
International Mouse Knockout Project StatusSrp72
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026549 VEGA Gene Model | MGI Sequence Detail 25255 C57BL/6J ±  kb
transcript OTTMUST00000065682 VEGA | MGI Sequence Detail 3625 Not Applicable 
polypeptide OTTMUSP00000032768 VEGA | MGI Sequence Detail 671 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(2) UniProt(7)
Polymorphisms SNPs within 2kb(123 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026270 Signal recognition particle, SRP72 subunit
InterPro IPR013699 Signal recognition particle, SRP72 subunit, RNA-binding
InterPro IPR011990 Tetratricopeptide-like helical
InterPro IPR019734 Tetratricopeptide repeat
InterPro IPR013026 Tetratricopeptide repeat-containing domain
Protein Ontology PR:000015627 signal recognition particle 72 kDa protein
References (Earliest) J:51619 Utz PJ, et al., The 72-kDa component of signal recognition particle is cleaved during apoptosis. J Biol Chem. 1998 Dec 25;273(52):35362-70
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:1913911, MGI:2140810, MGI:2141290, MGI:3039569

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory