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Mrpl22 Gene Detail
Summary
  • Symbol
    Mrpl22
  • Name
    mitochondrial ribosomal protein L22
  • Synonyms
    E030011D16Rik, HSPC158, MRP-L25, Rpml25
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333794
    NCBI Gene: 216767
  • Gene Overview
    MyGene.info: MRPL22
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:58171661-58179565 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 35.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    68 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333794
protein coding gene Chr11:58170043-58179580 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018344
protein coding gene Chr11:57846898-57854806 (+)
A/J MGP_AJ_G0018314
protein coding gene Chr11:55658099-55666002 (+)
AKR/J MGP_AKRJ_G0018283
protein coding gene Chr11:57483825-57491725 (+)
BALB/cJ MGP_BALBcJ_G0018285
protein coding gene Chr11:55998343-56006647 (+)
C3H/HeJ MGP_C3HHeJ_G0018096
protein coding gene Chr11:57416533-57424443 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018736
protein coding gene Chr11:59623287-59632426 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016386
protein coding gene Chr11:53008940-53016799 (+)
CAST/EiJ MGP_CASTEiJ_G0017661
protein coding gene Chr11:57513689-57522933 (+)
CBA/J MGP_CBAJ_G0018071
protein coding gene Chr11:62372557-62380454 (+)
DBA/2J MGP_DBA2J_G0018180
protein coding gene Chr11:55303737-55311670 (+)
FVB/NJ MGP_FVBNJ_G0018171
protein coding gene Chr11:55000758-55008675 (+)
LP/J MGP_LPJ_G0018255
protein coding gene Chr11:58382655-58390480 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018197
protein coding gene Chr11:63490531-63500154 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018779
protein coding gene Chr11:57525649-57533567 (+)
PWK/PhJ MGP_PWKPhJ_G0017433
protein coding gene Chr11:55909727-55917910 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017228
protein coding gene Chr11:57407283-57415161 (+)
WSB/EiJ MGP_WSBEiJ_G0017708
protein coding gene Chr11:57160168-57168082 (+)



Homology
more
  • Human Ortholog
    MRPL22, mitochondrial ribosomal protein L22
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MRPL22, mitochondrial ribosomal protein L22
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC158, L22mt, MRP-L22, MRP-L25, RPML25
  • Links
    NCBI Gene ID: 29093
    neXtProt AC: NX_Q9NWU5
    UniProt: Q9NWU5

  • Chr Location
    5q33.2; chr5:154941073-154969411 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 56664
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MRPL22
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020514 Ensembl Gene Model | MGI Sequence Detail 7905 C57BL/6J ±  kb
transcript ENSMUST00000020820 Ensembl | MGI Sequence Detail 722 Not Applicable  
polypeptide ENSMUSP00000020820 Ensembl | MGI Sequence Detail 206 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR005727 Ribosomal protein L22, bacterial/chloroplast-type
    IPR001063 Ribosomal protein L22/L17
    IPR036394 Ribosomal protein L22/L17 superfamily
Molecular
Reagents
less
  • All nucleic 61
    cDNA 61

    Microarray probesets 1
Other
Accession IDs
less
MGI:2442655
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory