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Rps19
Gene Detail
 Symbol
Name
ID
Rps19
ribosomal protein S19
MGI:1333780
Synonyms Dsk3
Feature Type protein coding gene
Genetic Map
Chromosome 7
13.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:24884371-24889806 bp, + strand
From VEGA annotation of GRCm38

  5436 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37416  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: ribosomal protein S19
Gene Tree: Rps19

Human
homologs
Human Homolog RPS19, ribosomal protein S19
NCBI Gene ID 6223
neXtProt AC  NX_P39019
Human Synonyms  DBA, DBA1, S19
Human Chr (Location)  19q13.2; chr19:41859918-41871416 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human RPS19
Alleles
and
phenotypes
All alleles(63) : Targeted(3) Gene trapped(59) Chemically induced(1)
 
Homozygous null embryos die prior to the formation of a blastocyst. Mice heterozygous for some point mutations show pigment defects affecting the feet and tail.
 
Gene Ontology
(GO)
classifications
All GO classifications: (29 annotations)
Process erythrocyte differentiation, maturation of SSU-rRNA, ...
Component cytoplasm, cytosol, ...
Function fibroblast growth factor binding, poly(A) RNA binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000022935 (Evidence)
Ensembl Gene ModelENSMUSG00000040952 (Evidence)
Entrez Gene20085 (Evidence)
DFCITC1573155, TC1589020
DoTSDT.102553259, DT.538034, DT.97367286
Consensus CDS ProjectCCDS20966.1
International Mouse Knockout Project StatusRps19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022935 VEGA Gene Model | MGI Sequence Detail 5436 C57BL/6J ±  kb
transcript OTTMUST00000055153 VEGA | MGI Sequence Detail 1284 Not Applicable 
polypeptide OTTMUSP00000026375 VEGA | MGI Sequence Detail 212 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(6) UniProt(7)
Polymorphisms SNPs within 2kb(33 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001266 Ribosomal protein S19e
InterPro IPR018277 Ribosomal protein S19e, conserved site
Protein Ontology PR:000014261 40S ribosomal protein S19
References (Earliest) J:52537 Draptchinskaia N, et al., The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia. Nat Genet. 1999 Feb;21(2):169-75
(Latest) J:177077 McGowan KA, et al., Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome. Blood. 2011 Sep 29;118(13):3622-33
All references(44)
Other
accession IDs
MGI:2450683

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory