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Ahrr Gene Detail
Summary
  • Symbol
    Ahrr
  • Name
    aryl-hydrocarbon receptor repressor
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333776
    NCBI Gene: 11624
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:74359237-74440450 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 40.15 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2320 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333776
 protein coding gene Chr13:74359237-74440450 (-)
129S1/SvImJ ENSMUSG00200011043
 protein coding gene Chr13:68750602-68845148 (-)
A/J ENSMUSG00195028380
 protein coding gene Chr13:69338696-69419809 (-)
AKR/J ENSMUSG00220036796
 protein coding gene Chr13:67930304-68010951 (-)
BALB/cJ ENSMUSG00180021976
 protein coding gene Chr13:69837040-69918133 (-)
C3H/HeJ ENSMUSG00175008040
 protein coding gene Chr13:70115819-70196420 (-)
C57BL/6NJ ENSMUSG00215010743
 protein coding gene Chr13:69903017-69984237 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018718
 protein coding gene Chr13:68866292-68948641 (-)
CAST/EiJ ENSTCUG00005011483
 protein coding gene Chr13:69421112-69500920 (-)
CBA/J ENSMUSG00210008793
 protein coding gene Chr13:69438322-69519528 (-)
DBA/2J ENSMUSG00185017871
 protein coding gene Chr13:73129875-73211081 (-)
FVB/NJ ENSMUSG00205024884
 protein coding gene Chr13:68817242-68898330 (-)
JF1/MsJ ENSUMUG00000027152
 protein coding gene Chr13:72891790-72971596 (-)
LP/J ENSMUSG00230025546
 protein coding gene Chr13:83048578-83129751 (-)
NOD/ShiLtJ ENSMUSG00190029638
 protein coding gene Chr13:69437260-69518345 (-)
NZO/HlLtJ ENSMUSG00225027641
 protein coding gene Chr13:75555814-75636901 (-)
PWK/PhJ ENSLUMG00010010867
 protein coding gene Chr13:68932929-69013129 (-)
SPRET/EiJ ENSMSPG00010029019
 protein coding gene Chr13:69830211-69917864 (-)
WSB/EiJ ENSIUOG00005019657
 protein coding gene Chr13:68691063-68770811 (-)



Homology
more
  • Human Ortholog
    AHRR, aryl hydrocarbon receptor repressor
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AHRR, aryl hydrocarbon receptor repressor
  • Synonyms
    AHH, AHHR, bHLHe77
  • Links
    NCBI Gene ID: 57491
    UniProt: A9YTQ3

  • Chr Location
    5p15.33; chr5:320682-438291 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit decreased susceptibility to chemically induced tumors.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • Tissues
    109
  • cDNA Data
    13
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 11624 NCBI Gene Model | MGI Sequence Detail 81214 C57BL/6J ±  kb
    transcript NM_009644 RefSeq | MGI Sequence Detail 4754 C57BL/6  
    polypeptide Q3U1U7 UniProt | EBI | MGI Sequence Detail 701 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 13
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 55
      Developmental Gene Expression 6
      Gene Ontology 7
      Phenotypes 17
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:351326 Weighardt H, et al., The aryl hydrocarbon receptor (AHR) repressor limits expression of antimicrobial genes but not AHR-dependent genes in intestinal eosinophils. J Leukoc Biol. 2024 May 3;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory