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Mab21l1
Gene Detail
 Symbol
Name
ID
Mab21l1
mab-21-like 1 (C. elegans)
MGI:1333773
Feature Type protein coding gene
Genetic Map
Chromosome 3
26.65 cM, cytoband E3-F1
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr3:55782510-55785285 bp, + strand
From Ensembl annotation of GRCm38

  2776 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36183  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Mab21l1

Human
homologs
Human Homolog MAB21L1, mab-21-like 1 (C. elegans)
NCBI Gene ID 4081
neXtProt AC  NX_Q13394
Human Synonyms  CAGR1
Human Chr (Location)  13q13; chr13:35473789-35476695 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from APF )
 
Homozygous mutation of this gene results in male infertility and eye developmental anomalies. Mutant eyes are small, absent of lens and iris, and display malformations of the retina.
 
Interactions
Mab21l1 interacts with 218 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process camera-type eye development, multicellular organismal development, ...
Component nucleus
External Resources: FuncBase
Expression
Literature Summary: (17 records)
Data Summary: Results (240)    Tissues (104)    Images (81)
Theiler Stages: 13, 15, 16, 17, 19, 20, 22, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 223
Northern blot 16
RT-PCR 1
cDNA source data(41)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(45) cDNA(43) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000056947 (Evidence)
Entrez Gene17116 (Evidence)
UniGene440209
DFCITC1580695, TC1680922
NIA Mouse Gene IndexU003252
Consensus CDS ProjectCCDS17360.1
International Mouse Knockout Project StatusMab21l1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056947 Ensembl Gene Model | MGI Sequence Detail 2776 C57BL/6J ±  kb
transcript ENSMUST00000075422 Ensembl | MGI Sequence Detail 2776 Not Applicable 
polypeptide ENSMUSP00000074878 Ensembl | MGI Sequence Detail 359 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms RFLP(1) : SNPs within 2kb(22 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024810 Mab-21 domain
InterPro IPR020950 Protein male abnormal 21-related
Protein Ontology PR:000010034 protein mab-21-like 1
References (Earliest) J:52199 Mariani M, et al., Mab21, the mouse homolog of a C. elegans cell-fate specification gene, participates in cerebellar, midbrain and eye development. Mech Dev. 1998 Dec;79(1-2):131-5
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(37)
Other
accession IDs
MGI:2139952

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory