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Pdcd6ip Gene Detail
Summary
  • Symbol
    Pdcd6ip
  • Name
    programmed cell death 6 interacting protein
  • Synonyms
    AIP1, Alix, mKIAA1375
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333753
    NCBI Gene: 18571
  • Gene Overview
    MyGene.info: PDCD6IP
Location & Maps
more
  • Sequence Map
    Chr9:113651744-113708259 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      56516 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 64.03 cM, cytoband F2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PDCD6IP, programmed cell death 6 interacting protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PDCD6IP, programmed cell death 6 interacting protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AIP1, ALIX, DRIP4, HP95
  • Links
    NCBI Gene ID: 10015
    neXtProt AC: NX_Q8WUM4

  • Chr Location
    3p22.3; chr3:33798571-33869707 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026168 VEGA Gene Model | MGI Sequence Detail 56516 C57BL/6J ±  kb
transcript OTTMUST00000064649 VEGA | MGI Sequence Detail 3223 Not Applicable  
polypeptide OTTMUSP00000032131 VEGA | MGI Sequence Detail 874 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    361 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000012458 programmed cell death 6-interacting protein
  • InterPro Domains
    IPR025304 ALIX V-shaped domain
    IPR004328 BRO1 domain
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 8
Other
Accession IDs
less
MGI:2143076, MGI:2143314, MGI:2143376
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 10
    Phenotypes 2
  • Earliest
    J:52190 Vito P, et al., Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction. J Biol Chem. 1999 Jan 15;274(3):1533-40
  • Latest
    J:193448 Baietti MF, et al., Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. Nat Cell Biol. 2012 Jul;14(7):677-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory