Trpt1
Gene Detail

Symbol Name ID

Trpt1 tRNA phosphotransferase 1 MGI:1333115

Synonyms

EST-MNCb3719, MGC:41710, TPT1, Tpt1h

Feature Type

protein coding gene

Genetic Map

Chromosome 19

5.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr19:6996131-6999044 bp, + strand From Ensembl annotation of GRCm38   2914 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:12878  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Trpt1

Human homologs

Human Homolog		TRPT1, tRNA phosphotransferase 1
NCBI Gene ID		83707
neXtProt AC		NX_Q86TN4
Human Chr (Location)		11q13.1; chr11:63991271-63993726 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(8) : Targeted(3) Gene trapped(5)
 

Mice homozygous for a knock-out allele exhibit normal glucose tolerance and translation of tyrosine-rich proteins.

 

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	regulation of protein kinase activity, tRNA processing, ...
Component	cellular_component
Function	2'-phosphotransferase activity, transferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (17)    Tissues (12)   
Theiler Stages: 26, 28

Assay Type	Results
Northern blot	17

cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(8) cDNA(7) Other(1)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000047656 (Evidence)
Entrez Gene	107328 (Evidence)
NIA Mouse Gene Index	U018995
EC	2.7.1.160
Consensus CDS Project	CCDS50375.1
International Mouse Knockout Project Status	Trpt1

Sequences

Length	Strain/Species
genomic	ENSMUSG00000047656	Ensembl Gene Model | MGI Sequence Detail	2914	C57BL/6J
transcript	ENSMUST00000088223	Ensembl | MGI Sequence Detail	1142	Not Applicable
polypeptide	ENSMUSP00000085555	Ensembl | MGI Sequence Detail	249	Not Applicable

All sequences(16) RefSeq(3) UniProt(1)

Polymorphisms

SNPs(1 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002745	Phosphotransferase KptA/Tpt1
Protein Ontology	PR:000016705	tRNA 2'-phosphotransferase 1

References

(Earliest) J:51223 Spinelli SL, et al., A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14136-41
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Other accession IDs

MGI:2147684, MGI:2183030