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Pigq Gene Detail
Summary
  • Symbol
    Pigq
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class Q
  • Synonyms
    Gpi1, Gpi1h, Gpi1p, Gpih
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333114
    NCBI Gene: 14755
  • Gene Overview
    MyGene.info: PIGQ
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:25926420-25942877 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 13.01 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    48 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333114
protein coding gene Chr17:25926420-25944510 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023382
protein coding gene Chr17:25038004-25057281 (-)
A/J MGP_AJ_G0023341
protein coding gene Chr17:24299074-24318769 (-)
AKR/J MGP_AKRJ_G0023307
protein coding gene Chr17:24412629-24430405 (-)
BALB/cJ MGP_BALBcJ_G0023346
protein coding gene Chr17:24530344-24548236 (-)
C3H/HeJ MGP_C3HHeJ_G0023106
protein coding gene Chr17:24792481-24812697 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023788
protein coding gene Chr17:26092137-26111284 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021264
protein coding gene Chr17:21764570-21782109 (-)
CAST/EiJ MGP_CASTEiJ_G0022608
protein coding gene Chr17:24687921-24705388 (-)
CBA/J MGP_CBAJ_G0023081
protein coding gene Chr17:27012505-27036353 (-)
DBA/2J MGP_DBA2J_G0023211
protein coding gene Chr17:23902686-23920464 (-)
FVB/NJ MGP_FVBNJ_G0023181
protein coding gene Chr17:23654025-23672066 (-)
LP/J MGP_LPJ_G0023288
protein coding gene Chr17:25328611-25348288 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023200
protein coding gene Chr17:26607327-26625301 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023828
protein coding gene Chr17:24729015-24750596 (-)
PWK/PhJ MGP_PWKPhJ_G0022357
protein coding gene Chr17:22677848-22695999 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022175
protein coding gene Chr17:22809802-22828227 (-)
WSB/EiJ MGP_WSBEiJ_G0022671
protein coding gene Chr17:24783498-24803430 (-)



Homology
more
  • Human Ortholog
    PIGQ, phosphatidylinositol glycan anchor biosynthesis class Q
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PIGQ, phosphatidylinositol glycan anchor biosynthesis class Q
    Orthology source: HomoloGene, HGNC
  • Synonyms
    c407A10.1, GPI1
  • Links
    NCBI Gene ID: 9091
    neXtProt AC: NX_Q9BRB3
    UniProt: Q9BRB3

  • Chr Location
    16p13.3; chr16:569968-584136 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 31228
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PIGQ
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14755 NCBI Gene Model | MGI Sequence Detail 16458 C57BL/6J ±  kb
transcript NM_001291025 RefSeq | MGI Sequence Detail 3295 C57BL/6  
polypeptide Q9QYT7 UniProt | EBI | MGI Sequence Detail 581 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    16 Sequences
  • EC
  • InterPro Domains
    IPR007720 N-acetylglucosaminyl transferase component
Molecular
Reagents
less
  • All nucleic 154
    cDNA 154

    Microarray probesets 11
Other
Accession IDs
less
MGI:1345628
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:50634 Tiede A, et al., Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. Biochem J. 1998 Sep 15;334(Pt 3):609-16
  • Latest
    J:194116 Flachs P, et al., Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. PLoS Genet. 2012;8(11):e1003044

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory