Pigq
Gene Detail

Symbol Name ID

Pigq phosphatidylinositol glycan anchor biosynthesis, class Q MGI:1333114

Synonyms

Gpi1, Gpi1h, Gpi1p, Gpih

Feature Type

protein coding gene

Genetic Map

Chromosome 17

13.01 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr17:25926427-25944510 bp, - strand From VEGA annotation of GRCm38   18084 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:31228  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 zebrafish

Gene Tree: Pigq

Human homologs

Human Homolog		PIGQ, phosphatidylinositol glycan anchor biosynthesis, class Q
NCBI Gene ID		9091
neXtProt AC		NX_Q9BRB3
Human Synonyms		c407A10.1, GPI1
Human Chr (Location)		16p13.3; chr16:619968-634136 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(11) : Targeted(3) Gene trapped(8)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	GPI anchor biosynthetic process
Component	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex, integral to membrane, ...
Function	phosphatidylinositol N-acetylglucosaminyltransferase activity, transferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (117)    Tissues (96)    Images (36)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	117

cDNA source data(148)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(150) cDNA(150)
Microarray probesets(11)

Other database links

VEGA Gene Model	OTTMUSG00000033060 (Evidence)
Ensembl Gene Model	ENSMUSG00000025728 (Evidence)
Entrez Gene	14755 (Evidence)
UniGene	362054
DFCI	TC1571997, TC1598305, TC1607897, TC1747975
DoTS	DT.110548971, DT.110548986, DT.492935, DT.91403582, DT.94342833, DT.94362491, DT.94362508, DT.97414402, DT.99864217
EC	2.4.1.198
Consensus CDS Project	CCDS28538.1
International Mouse Knockout Project Status	Pigq

Sequences

Length	Strain/Species
genomic	OTTMUSG00000033060	VEGA Gene Model | MGI Sequence Detail	18084	C57BL/6J
transcript	OTTMUST00000082548	VEGA | MGI Sequence Detail	3233	Not Applicable
polypeptide	OTTMUSP00000044251	VEGA | MGI Sequence Detail	641	Not Applicable

All sequences(108) RefSeq(2) UniProt(10)

Polymorphisms

SNPs(47 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007720	N-acetylglucosaminyl transferase component
Protein Ontology	PR:000012704	phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

References

(Earliest) J:50634 Tiede A, et al., Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. Biochem J. 1998 Sep 15;334(Pt 3):609-16
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Other accession IDs

MGI:1345628