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Pigq Gene Detail
Summary
  • Symbol
    Pigq
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class Q
  • Synonyms
    Gpi1, Gpi1h, Gpi1p, Gpih
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333114
    NCBI Gene: 14755
  • Gene Overview
    MyGene.info: PIGQ
Location & Maps
more
  • Sequence Map
    Chr17:25926421-25944510 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18090 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 13.01 cM, cytoband B
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PIGQ, phosphatidylinositol glycan anchor biosynthesis class Q
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PIGQ, phosphatidylinositol glycan anchor biosynthesis class Q
    Orthology source: HGNC, HomoloGene
  • Synonyms
    c407A10.1, GPI1
  • Links
    NCBI Gene ID: 9091
    neXtProt AC: NX_Q9BRB3

  • Chr Location
    16p13.3; chr16:569968-584136 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 31228
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PIGQ
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    13
  • Gene trapped
    8
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    2 involving Pigq
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033060 VEGA Gene Model | MGI Sequence Detail 18090 C57BL/6J ±  kb
transcript OTTMUST00000082548 VEGA | MGI Sequence Detail 3233 Not Applicable  
polypeptide OTTMUSP00000044251 VEGA | MGI Sequence Detail 641 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    48 from dbSNP Build 142
Protein
Information
less
  • UniProt
    16 Sequences
  • Protein Ontology
    PR:000012704 phosphatidylinositol N-acetylglucosaminyltransferase subunit Q
  • EC
  • InterPro Domains
    IPR007720 N-acetylglucosaminyl transferase component
Molecular
Reagents
less
  • All nucleic 152
    cDNA 152

    Microarray probesets 11
Other
Accession IDs
less
MGI:1345628
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:50634 Tiede A, et al., Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. Biochem J. 1998 Sep 15;334(Pt 3):609-16
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory