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Ran
Gene Detail
 Symbol
Name
ID
Ran
RAN, member RAS oncogene family
MGI:1333112
Feature Type protein coding gene
Genetic Map
Chromosome 5
67.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:129020069-129024323 bp, + strand
From VEGA annotation of GRCm38

  4255 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68143  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: GTP-binding nuclear protein RAN
Gene Tree: Ran

Human
homologs
Human Homolog RAN, RAN, member RAS oncogene family
NCBI Gene ID 5901
neXtProt AC  NX_P62826
Human Synonyms  ARA24, Gsp1, TC4
Human Chr (Location)  12q24.3; chr12:130872072-130877656 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(36) : Gene trapped(34) Targeted(2)
Interactions
Ran interacts with 272 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (35 annotations)
Process actin cytoskeleton organization, cell cycle, ...
Component chromatin, cytoplasm, ...
Function GDP binding, GTPase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (113)    Tissues (94)    Images (40)
Theiler Stages: 1, 10, 11, 12, 13, 14, 15, 16, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28
Assay TypeResults
Immunohistochemistry 2
RNA in situ 111
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(22) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000016923 (Evidence)
Ensembl Gene ModelENSMUSG00000029430 (Evidence)
Entrez Gene19384 (Evidence)
DFCITC1573705, TC1714383, TC1741487
Consensus CDS ProjectCCDS19693.1
International Mouse Knockout Project StatusRan
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016923 VEGA Gene Model | MGI Sequence Detail 4255 C57BL/6J ±  kb
transcript OTTMUST00000041051 VEGA | MGI Sequence Detail 2377 Not Applicable 
polypeptide OTTMUSP00000018390 VEGA | MGI Sequence Detail 216 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(42 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR002041 Ran GTPase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013708 GTP-binding nuclear protein Ran
References (Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:198839 Nagai M, et al., Downregulation of the small GTPase ras-related nuclear protein accelerates cellular ageing. Biochim Biophys Acta. 2013 Mar;1830(3):2813-9
All references(56)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory