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Phtf1 Gene Detail
Summary
  • Symbol
    Phtf1
  • Name
    putative homeodomain transcription factor 1
  • Synonyms
    Phft
  • Feature Type
    protein coding gene
  • IDs
    MGI:1332671
    NCBI Gene: 18685
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:103875426-103914806 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 45.52 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1332671
 protein coding gene Chr3:103875426-103931914 (+)
129S1/SvImJ ENSMUSG00200040304
 protein coding gene Chr3:100484451-100540946 (+)
A/J ENSMUSG00195046264
 protein coding gene Chr3:100898051-100954545 (+)
AKR/J ENSMUSG00220036925
 protein coding gene Chr3:99258062-99314556 (+)
BALB/cJ ENSMUSG00180034515
 protein coding gene Chr3:100825586-100882148 (+)
C3H/HeJ ENSMUSG00175025187
 protein coding gene Chr3:100380367-100436860 (+)
C57BL/6NJ ENSMUSG00215017682
 protein coding gene Chr3:101145332-101201819 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025460
 protein coding gene Chr3:98041673-98109963 (+)
CAST/EiJ ENSTCUG00005018912
 protein coding gene Chr3:101104462-101160963 (+)
CBA/J ENSMUSG00210050685
 protein coding gene Chr3:101002399-101058893 (+)
DBA/2J ENSMUSG00185021577
 protein coding gene Chr3:101481510-101537998 (+)
FVB/NJ ENSMUSG00205024942
 protein coding gene Chr3:100063106-100119599 (+)
JF1/MsJ ENSUMUG00000032682
 protein coding gene Chr3:100234370-100293510 (+)
LP/J ENSMUSG00230015639
 protein coding gene Chr3:103412778-103469271 (+)
NOD/ShiLtJ ENSMUSG00190044223
 protein coding gene Chr3:101677582-101734147 (+)
NZO/HlLtJ ENSMUSG00225018663
 protein coding gene Chr3:105879343-105935907 (+)
PWK/PhJ ENSLUMG00010027197
 protein coding gene Chr3:100295051-100351577 (+)
SPRET/EiJ ENSMSPG00010039980
 protein coding gene Chr3:100511754-100554113 (+)
WSB/EiJ ENSIUOG00005030328
 protein coding gene Chr3:101023145-101079651 (+)



Homology
more
  • Human Ortholog
    PHTF1, putative homeodomain transcription factor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHTF1, putative homeodomain transcription factor 1
  • Synonyms
    PHTF
  • Links
    NCBI Gene ID: 10745
    UniProt: Q9UMS5

  • Chr Location
    1p13.2; chr1:113696052-113759908 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    754
  • Tissues
    114
  • cDNA Data
    61
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 18685 NCBI Gene Model | MGI Sequence Detail 39381 C57BL/6J ±  kb
    transcript NM_013629 RefSeq | MGI Sequence Detail 3342 C57BL/6  
    polypeptide Q9QZ09 UniProt | EBI | MGI Sequence Detail 761 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 64
      cDNA 62
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2139909, MGI:2139960
    References
    more
    • Summaries
      All 53
      Developmental Gene Expression 9
      Diseases 1
      Gene Ontology 4
      Phenotypes 13
    • Earliest
      J:59377 Raich N, et al., PHTF, a novel atypical homeobox gene on chromosome 1p13, is evolutionarily conserved. Genomics. 1999 Jul 1;59(1):108-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory