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Ugcg
Gene Detail
Symbol

Name
ID
Ugcg
UDP-glucose ceramide glucosyltransferase
MGI:1332243
Synonyms
Epcs21, GlcT-1, Ugcgl
Feature Type
protein coding gene
Genetic Map
Chromosome 4
32.44 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:59189257-59222833 bp, + strand
From VEGA annotation of GRCm38

  33577 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37763  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ugcg

Human
homologs
Human Homolog UGCG, UDP-glucose ceramide glucosyltransferase
NCBI Gene ID 7357
neXtProt AC  NX_Q16739
Human Synonyms  GCS, GLCT1
Human Chr (Location)  9q31; chr9:111896926-111935369 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(7) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
At embryonic day 7.5, embryos homozygous for a null mutation exhibit decreased size, markedly reduced extraembryonic tissues and a large increase in cells undergoing apoptosis. Mutants die by embryonic day 8.5.
 
Interactions
Ugcg interacts with 367 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (110)    Tissues (109)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
In situ reporter (knock in) 9
RT-PCR 7
cDNA source data(107)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(111) Genomic(2) cDNA(107) Primer pair(1) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000007645 (Evidence)
Ensembl Gene ModelENSMUSG00000028381 (Evidence)
Entrez Gene22234 (Evidence)
UniGene198803
DFCITC1574414
DoTSDT.97399586, DT.94336815, DT.91422495, DT.101407788
NIA Mouse Gene IndexU004376
EC2.4.1.80
Consensus CDS ProjectCCDS18219.1
International Mouse Knockout Project StatusUgcg
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007645 VEGA Gene Model | MGI Sequence Detail 33577 C57BL/6J ±  kb
transcript OTTMUST00000017544 VEGA | MGI Sequence Detail 4012 Not Applicable 
polypeptide OTTMUSP00000008102 VEGA | MGI Sequence Detail 394 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(4) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(125 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025993 Ceramide glucosyltransferase
Protein Ontology PR:000017043 ceramide glucosyltransferase
References
(Earliest) J:48204 Ichikawa S, et al., Molecular cloning and expression of mouse ceramide glucosyltransferase. Biochem Mol Biol Int. 1998 May;44(6):1193-202
(Latest) J:213489 Porubsky S, et al., Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure. J Pathol. 2014 Sep;234(1):120-33
All references(54)
Other
accession IDs
MGI:1860296, MGI:2140489, MGI:2140685

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory