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Cds2
Gene Detail
Symbol

Name
ID
Cds2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
MGI:1332236
Synonyms
5730450N06Rik, 5730460C18Rik, D2Wsu127e
Feature Type
protein coding gene
Genetic Map
Chromosome 2
64.15 cM, cytoband G1
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr2:132263148-132312050 bp, + strand
From VEGA annotation of GRCm38

  48903 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37854  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phosphatidate cytidylyltransferase, eukaryotic type
Gene Tree: Cds2

Human
homologs
Human Homolog CDS2, CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
NCBI Gene ID 8760
neXtProt AC  NX_O95674
Human Chr (Location)  20p13; chr20:5126761-5197887 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(134) : Gene trapped(132) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display a lethal phenotype. Heterozygotes show a distorted lymphocyte distribution and enhanced sensorimotor gating.
 
Interactions
Cds2 interacts with 447 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (170)    Tissues (143)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 157
Northern blot 7
RT-PCR 6
cDNA source data(158)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(159) cDNA(158) Primer pair(1)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000015552 (Evidence)
Ensembl Gene ModelENSMUSG00000058793 (Evidence)
Entrez Gene110911 (Evidence)
UniGene284503
DFCITC1575805, TC1589501, TC1644116, TC1671368
DoTSDT.101722865, DT.101360935, DT.530989, DT.97391403, DT.103576033
NIA Mouse Gene IndexU002502
EC2.7.7.41
Consensus CDS ProjectCCDS16772.1, CCDS71150.1
International Mouse Knockout Project StatusCds2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015552 VEGA Gene Model | MGI Sequence Detail 48903 C57BL/6J ±  kb
transcript OTTMUST00000036944 VEGA | MGI Sequence Detail 8396 Not Applicable 
polypeptide OTTMUSP00000016575 VEGA | MGI Sequence Detail 444 Not Applicable 

For the selected sequences
All sequences(85) RefSeq(6) UniProt(13)
Polymorphisms
SNPs within 2kb(476 from dbSNP Build 137)    SNPs within 2kb including multiple locations(480)
Protein-related
information
ResourceIDDescription
InterPro IPR000374 Phosphatidate cytidylyltransferase
InterPro IPR016720 Phosphatidate cytidylyltransferase, eukaryota
Protein Ontology PR:000005291 phosphatidate cytidylyltransferase 2
References
(Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(46)
Other
accession IDs
MGD-MRK-35819, MGI:107353, MGI:1917815, MGI:1924099, MGI:2139105

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory