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Zfp148
Gene Detail
 Symbol
Name
ID
Zfp148
zinc finger protein 148
MGI:1332234
Synonyms 2210405J08Rik, BERF-1, beta enolase repressor factor 1, BFCOL1, ZBP-89
Feature Type protein coding gene
Genetic Map
Chromosome 16
23.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:33380775-33503903 bp, + strand
From NCBI annotation of GRCm38

  123129 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8003  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Zfp148

Human
homologs
Human Homolog ZNF148, zinc finger protein 148
NCBI Gene ID 7707
neXtProt AC  NX_Q9UQR1
Human Synonyms  BERF-1, BFCOL1, HT-BETA, pHZ-52, ZBP-89, ZFP148
Human Chr (Location)  3q21; chr3:125225669-125375354 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(139) : Gene trapped(133) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Disruption of one allele results in haploinsufficient male infertility in which chimeric males display a loss of germ cells.
 
Interactions
Zfp148 interacts with 547 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process gamete generation, negative regulation of gene expression, ...
Component nucleus
Function DNA binding, double-stranded DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (40)    Tissues (39)    Images (4)
Theiler Stages: 2, 3, 4, 5, 15, 17, 19, 21, 23, 28
Assay TypeResults
RNA in situ 32
RT-PCR 8
cDNA source data(168)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(172) cDNA(168) Primer pair(4)
Microarray probesets(12)
Other database
links
Ensembl Gene ModelENSMUSG00000022811 (Evidence)
Entrez Gene22661 (Evidence)
UniGene392667
DFCITC1577621, TC1583878, TC1652506, TC1653590, TC1682454
DoTSDT.101310872, DT.101391885, DT.527917
NIA Mouse Gene IndexU017038
Consensus CDS ProjectCCDS28130.1
International Mouse Knockout Project StatusZfp148
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 22661 NCBI Gene Model | MGI Sequence Detail 123129 C57BL/6J ±  kb
transcript NM_011749 RefSeq | MGI Sequence Detail 9431 C57BL/6 
polypeptide Q61624 UniProt | EBI | MGI Sequence Detail 794 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(16) UniProt(7)
Polymorphisms PCR(1) : SNPs within 2kb(532 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017718 zinc finger protein 148
Graphical View of Protein Domain Structure
References (Earliest) J:38556 Hasegawa T, et al., Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes. J Biol Chem. 1997 Feb 21;272(8):4915-23
(Latest) J:206932 Li X, et al., Stress Hematopoiesis Is Regulated by the Kruppel-Like Transcription Factor ZBP-89. Stem Cells. 2014 Mar;32(3):791-801
All references(55)
Other
accession IDs
MGI:1925897, MGI:2146444, MGI:2146606

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory