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Igkv8-21 Gene Detail
Summary
  • Symbol
    Igkv8-21
  • Name
    immunoglobulin kappa variable 8-21
  • Feature Type
    gene segment
  • IDs
    MGI:1330840
    NCBI Gene: 620400
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:70291879-70292436 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 31.85 cM
Strain
Comparison
more
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330840
gene segment Chr6:70291879-70292456 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000166
gene segment Chr6:70460374-70460951 (-)
A/J MGP_AJ_G0000153
gene segment Chr6:67924889-67925466 (-)
AKR/J MGP_AKRJ_G0000147
gene segment Chr6:69633120-69633697 (-)
BALB/cJ MGP_BALBcJ_G0000146
gene segment Chr6:68036816-68037393 (-)
C3H/HeJ MGP_C3HHeJ_G0000103
gene segment Chr6:114308002-114308579 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0000144
gene segment Chr6:66737690-66738267 (-)
LP/J MGP_LPJ_G0000179
gene segment Chr6:70571615-70572192 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0000153
gene segment Chr6:79020038-79020615 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0000130
gene segment Chr4:49441120-49441697 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Synonyms
    B3, IGKV41
  • Links
    NCBI Gene ID: 28908
    UniProt: P06312

  • Chr Location
    2p11.2; chr2:88885572-88886153 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 620400 NCBI Gene Model | MGI Sequence Detail 558 C57BL/6J ±  kb
polypeptide A0A140T8P7 UniProt | EBI | MGI Sequence Detail 120 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    Genomic 5
References
more
  • Summaries
    All 7
    Gene Ontology 1
  • Earliest
    J:47632 Kirschbaum T, et al., The 3' part of the immunoglobulin kappa locus of the mouse. Eur J Immunol. 1998 May;28(5):1458-66
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/03/2022
MGI 6.21
The Jackson Laboratory