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Atp10a Gene Detail
Summary
  • Symbol
    Atp10a
  • Name
    ATPase, class V, type 10A
  • Synonyms
    Atp10c, pfatp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330809
    NCBI Gene: 11982
  • Gene Overview
    MyGene.info: ATP10A
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:58656166-58829420 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 33.88 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2073 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330809
protein coding gene Chr7:58656142-58830244 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032321
protein coding gene Chr7:59485674-59664160 (+)
A/J MGP_AJ_G0032300
protein coding gene Chr7:58604854-58777972 (+)
AKR/J MGP_AKRJ_G0032236
protein coding gene Chr7:59897410-60079035 (+)
BALB/cJ MGP_BALBcJ_G0032312
protein coding gene Chr7:58155771-58330971 (+)
C3H/HeJ MGP_C3HHeJ_G0032025
protein coding gene Chr7:60287306-60465655 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032805
protein coding gene Chr7:62187444-62370624 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029812
protein coding gene Chr7:61076082-61251055 (+)
CAST/EiJ MGP_CASTEiJ_G0031354
protein coding gene Chr7:51459249-51641749 (+)
CBA/J MGP_CBAJ_G0031990
protein coding gene Chr7:64341126-64536198 (+)
DBA/2J MGP_DBA2J_G0032147
protein coding gene Chr7:57544489-57719554 (+)
FVB/NJ MGP_FVBNJ_G0032101
protein coding gene Chr7:57514296-57693862 (+)
LP/J MGP_LPJ_G0032228
protein coding gene Chr7:60613940-60794489 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032138
protein coding gene Chr7:63933443-64119567 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032822
protein coding gene Chr7:58960668-59137884 (+)
PWK/PhJ MGP_PWKPhJ_G0031074
protein coding gene Chr7:50763212-50940693 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030915
protein coding gene Chr7:46929933-47104741 (+)
WSB/EiJ MGP_WSBEiJ_G0031472
protein coding gene Chr7:59537984-59717536 (+)



Homology
more
  • Human Ortholog
    ATP10A, ATPase phospholipid transporting 10A (putative)
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ATP10A, ATPase phospholipid transporting 10A (putative)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATP10C, ATPVA, ATPVC
  • Links
    NCBI Gene ID: 57194
    neXtProt AC: NX_O60312
    UniProt: O60312

  • Chr Location
    15q12; chr15:25672241-25865144 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 56461
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ATP10A
  • Gene Tree
Human Diseases
less
  • References
    5 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    32 phenotype references
Disruption of this gene at the distal end of the p23DFiOD deletion may be responsible for the obesity phenotypes associated with that deletion.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025324 Ensembl Gene Model | MGI Sequence Detail 173255 C57BL/6J ±  kb
transcript ENSMUST00000168747 Ensembl | MGI Sequence Detail 5419 Not Applicable  
polypeptide ENSMUSP00000129811 Ensembl | MGI Sequence Detail 1508 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 47
    Primer pair 3

    Microarray probesets 3
References
more
  • Summaries
    All 64
    Developmental Gene Expression 6
    Diseases 5
    Gene Ontology 5
    Phenotypes 32
  • Earliest
    J:29903 Russell LB, et al., Complementation analyses for 45 mutations encompassing the pink-eyed dilution (p) locus of the mouse. Genetics. 1995 Dec;141(4):1547-62
  • Latest
    J:260252 Nakai N, et al., Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice. Sci Adv. 2017 Jun;3(6):e1603001

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory