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Sprr2a1 Gene Detail
Summary
  • Symbol
    Sprr2a1
  • Name
    small proline-rich protein 2A1
  • Synonyms
    Sprr2a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330350
    NCBI Gene: 20755
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr3:92215799-92221911 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330350
protein coding gene Chr3:92215799-92222491 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0027452
protein coding gene Chr3:89763198-89766482 (+)
AKR/J MGP_AKRJ_G0027419
protein coding gene Chr3:91944052-91947724 (+)
BALB/cJ MGP_BALBcJ_G0027461
protein coding gene Chr3:89530353-89618886 (+)
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0026650
protein coding gene Chr3:91496447-91499830 (+)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0027304
protein coding gene Chr3:105793709-105798386 (+)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0026382
protein coding gene Chr3:88996061-89001627 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026201
protein coding gene Chr3:89958164-89961401 (+)
WSB/EiJ MGP_WSBEiJ_G0026730
protein coding gene Chr3:91924527-91929389 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Sprr2a1
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078664 Ensembl Gene Model | MGI Sequence Detail 6113 C57BL/6J ±  kb
transcript ENSMUST00000074449 Ensembl | MGI Sequence Detail 3003 Not Applicable  
polypeptide ENSMUSP00000083330 Ensembl | MGI Sequence Detail 83 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 21
    Genomic 5
    cDNA 16

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 9
    Diseases 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:113697 Gibbs S, et al., Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins. Genomics. 1993 Jun;16(3):630-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory