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Magoh
Gene Detail
 Symbol
Name
ID
Magoh
mago-nashi homolog, proliferation-associated (Drosophila)
MGI:1330312
Synonyms Mago-m, Mos2
Feature Type protein coding gene
Genetic Map
Chromosome 4
50.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr4:107879755-107887424 bp, + strand
From VEGA annotation of GRCm38

  7670 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1776  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: mago nashi-like protein
Gene Tree: Magoh

Human
homologs
Human Homolog MAGOH, mago-nashi homolog, proliferation-associated (Drosophila)
NCBI Gene ID 4116
neXtProt AC  NX_P61326
Human Synonyms  MAGOH1, MAGOHA
Human Chr (Location)  1p32.3; chr1:53226892-53238610 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Chemically induced (ENU)(1) Gene trapped(4) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Phenotype (Marker Detail Clip): Homozygous null mutation in this gene is embryonic lethal and heterozygous mice are postnatal lethal with incomplete penetrance with reduced body size and microcephaly.
 
Interactions
Magoh interacts with 52 markers (Mir16-2, Mir98, Mir188, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process female gamete generation, mRNA processing, ...
Component catalytic step 2 spliceosome, cytoplasm, ...
Function poly(A) RNA binding, RNA binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (18)    Tissues (11)   
Theiler Stages: 23, 24, 25, 27, 28
Assay TypeResults
RNA in situ 1
RT-PCR 17
cDNA source data(67)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(68) cDNA(67) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000009191 (Evidence)
Ensembl Gene ModelENSMUSG00000028609 (Evidence)
Entrez Gene17149 (Evidence)
UniGene808
DFCITC1575503
DoTSDT.493303, DT.97398468
NIA Mouse Gene IndexU004610
Consensus CDS ProjectCCDS18441.1
International Mouse Knockout Project StatusMagoh
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009191 VEGA Gene Model | MGI Sequence Detail 7670 C57BL/6J ±  kb
transcript OTTMUST00000020785 VEGA | MGI Sequence Detail 692 Not Applicable 
polypeptide OTTMUSP00000009528 VEGA | MGI Sequence Detail 146 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(54 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004023 Mago nashi protein
Protein Ontology PR:000010086 protein mago nashi
References (Earliest) J:113667 Newmark PA, et al., mago nashi mediates the posterior follicle cell-to-oocyte signal to organize axis formation in Drosophila. Development. 1997 Aug;124(16):3197-207
(Latest) J:194281 Silver DL, et al., The EJC component Magoh regulates proliferation and expansion of neural crest-derived melanocytes. Dev Biol. 2013 Mar 15;375(2):172-81
All references(34)
Other
accession IDs
MGI:3822488

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory