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Trpm1
Gene Detail
 Symbol
Name
ID
Trpm1
transient receptor potential cation channel, subfamily M, member 1
MGI:1330305
Synonyms 4732499L03Rik, LTRPC1, melastatin, Mlsn1
Feature Type protein coding gene
Genetic Map
Chromosome 7
34.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:64153835-64269775 bp, + strand
From VEGA annotation of GRCm38

  115941 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19940  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: transient receptor potential cation channels TRPM1/TRPM3
Gene Tree: Trpm1

Human
homologs
Human Homolog TRPM1, transient receptor potential cation channel, subfamily M, member 1
NCBI Gene ID 4308
neXtProt AC  NX_Q7Z4N2
Human Synonyms  CSNB1C, LTRPC1, MLSN1
Human Chr (Location)  15q13.3; chr15:31001061-31161273 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human TRPM1
Alleles
and
phenotypes
All alleles(4) : Targeted(3) Gene trapped(1)
 
Homozygous mutants have defects in rod and cone electrophysiology affecting the photoresponses.
 
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process calcium ion transmembrane transport, calcium ion transport into cytosol, ...
Component cell, integral component of membrane, ...
Function calcium channel activity, cation channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (99)    Tissues (48)    Images (23)
Theiler Stages: 19, 20, 21, 22, 25, 26, 28
Assay TypeResults
RNA in situ 71
RT-PCR 28
cDNA source data(40)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(49) Genomic(3) cDNA(41) Primer pair(4) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000022613 (Evidence)
Ensembl Gene ModelENSMUSG00000030523 (Evidence)
Entrez Gene17364 (Evidence)
UniGene38875
NIA Mouse Gene IndexU008177
Consensus CDS ProjectCCDS21332.2, CCDS39975.2
International Mouse Knockout Project StatusTrpm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022613 VEGA Gene Model | MGI Sequence Detail 115941 C57BL/6J ±  kb
transcript OTTMUST00000054157 VEGA | MGI Sequence Detail 5076 Not Applicable 
polypeptide OTTMUSP00000025807 VEGA | MGI Sequence Detail 1628 Not Applicable 

For the selected sequences
All sequences(483) RefSeq(6) UniProt(7)
Polymorphisms PCR(1) : SNPs within 2kb(1184 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1186)
Protein-related
information
ResourceIDDescription
InterPro IPR005821 Ion transport domain
Protein Ontology PR:000016697 transient receptor potential cation channel subfamily M member 1
References (Earliest) J:51031 Hunter JJ, et al., Chromosomal localization and genomic characterization of the mouse melastatin gene (Mlsn1). Genomics. 1998 Nov 15;54(1):116-23
(Latest) J:205780 Xiong WH, et al., Serum TRPM1 autoantibodies from melanoma associated retinopathy patients enter retinal on-bipolar cells and attenuate the electroretinogram in mice. PLoS One. 2013;8(8):e69506
All references(53)
Other
accession IDs
MGI:2142011, MGI:3036274

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory