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Zpr1
Gene Detail
 Symbol
Name
ID
Zpr1
ZPR1 zinc finger
MGI:1330262
Synonyms Zfp259, ZPR1
Feature Type protein coding gene
Genetic Map
Chromosome 9
25.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:46273064-46282643 bp, + strand
From VEGA annotation of GRCm38

  9580 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2900  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: zinc-finger protein ZPR1
Gene Tree: Zpr1

Human
homologs
Human Homolog ZPR1, ZPR1 zinc finger
NCBI Gene ID 8882
neXtProt AC  NX_O75312
Human Synonyms  ZNF259
Human Chr (Location)  11q23.3; chr11:116778560-116788023 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display embryonic lethality, fail to form a normal trophectoderm and fail to expand the inner cell mass.
 
Interactions
Zpr1 interacts with 186 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (48 annotations)
Process apoptotic process involved in development, axon development, ...
Component axon, Cajal body, ...
Function metal ion binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (22)    Tissues (22)    Images (2)
Theiler Stages: 17, 23, 28
Assay TypeResults
RNA in situ 14
Northern blot 8
cDNA source data(74)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(74) cDNA(74)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000021886 (Evidence)
Ensembl Gene ModelENSMUSG00000032078 (Evidence)
Entrez Gene22687 (Evidence)
UniGene17519
DFCITC1576217, TC1589790, TC1605317
DoTSDT.101356570, DT.101375355, DT.110615950, DT.531254
NIA Mouse Gene IndexU010437
PDB2QKD
Consensus CDS ProjectCCDS23144.1
International Mouse Knockout Project StatusZpr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021886 VEGA Gene Model | MGI Sequence Detail 9580 C57BL/6J ±  kb
transcript OTTMUST00000051963 VEGA | MGI Sequence Detail 2984 Not Applicable 
polypeptide OTTMUSP00000024540 VEGA | MGI Sequence Detail 459 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(2) UniProt(10)
Polymorphisms SNPs within 2kb(90 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004457 Zinc finger, ZPR1-type
Protein Ontology PR:000017785 zinc finger protein ZPR1
References (Earliest) J:50499 Galcheva-Gargova Z, et al., Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor. Science. 1996 Jun 21;272(5269):1797-802
(Latest) J:184463 Ahmad S, et al., The zinc finger protein ZPR1 is a potential modifier of spinal muscular atrophy. Hum Mol Genet. 2012 Jun 15;21(12):2745-58
All references(37)
Other
accession IDs
MGI:2143010

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory