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Dpm1
Gene Detail
 Symbol
Name
ID
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
MGI:1330239
Feature Type protein coding gene
Genetic Map
Chromosome 2
88.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:168209048-168230591 bp, - strand
From VEGA annotation of GRCm38

  21544 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2865  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: dolichyl-phosphate beta-D-mannosyltransferase
Gene Tree: Dpm1

Human
homologs
Human Homolog DPM1, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
NCBI Gene ID 8813
neXtProt AC  NX_O60762
Human Synonyms  CDGIE, MPDS
Human Chr (Location)  20q13.13; chr20:50934867-50958544 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human DPM1
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process dolichol metabolic process, GDP-mannose metabolic process, ...
Component dolichol-phosphate-mannose synthase complex, endoplasmic reticulum, ...
Function alcohol binding, dolichyl-phosphate beta-D-mannosyltransferase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (109)    Tissues (107)    Images (15)
Theiler Stages: 2, 3, 4, 5, 22, 28
Assay TypeResults
RNA in situ 94
RT-PCR 15
cDNA source data(84)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(85) cDNA(84) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000016047 (Evidence)
Ensembl Gene ModelENSMUSG00000078919 (Evidence)
Entrez Gene13480 (Evidence)
UniGene422657
DFCITC1576499
Consensus CDS ProjectCCDS17109.1
International Mouse Knockout Project StatusDpm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016047 VEGA Gene Model | MGI Sequence Detail 21544 C57BL/6J ±  kb
transcript OTTMUST00000038290 VEGA | MGI Sequence Detail 2293 Not Applicable 
polypeptide OTTMUSP00000017164 VEGA | MGI Sequence Detail 260 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(2)
Polymorphisms SNPs within 2kb(56 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000006656 dolichol-phosphate mannosyltransferase
References (Earliest) J:50821 Tomita S, et al., A homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for synthesis of dolichol-phosphate-mannose in mammalian cells. J Biol Chem. 1998 Apr 10;273(15):9249-54
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)
Other
accession IDs
MGI:2138839, MGI:2138855

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory