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Dpm1
Gene Detail
Symbol

Name
ID
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
MGI:1330239
Feature Type
protein coding gene
Genetic Map
Chromosome 2
88.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:168209048-168230591 bp, - strand
From VEGA annotation of GRCm38

  21544 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2865  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DPM1
Protein SuperFamily: dolichyl-phosphate beta-D-mannosyltransferase
Gene Tree: Dpm1

Human
homologs
DPM1, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 8813
neXtProt AC: NX_O60762

Human Synonyms: CDGIE, MPDS

Human Chr (Location): 20q13.13; chr20:50934855-50958561 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DPM1

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Dpm1 interacts with 241 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (102)    Tissues (102)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
RT-PCR 8
cDNA source data(84)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dpm1    NEW 
Molecular
reagents
All nucleic(85) cDNA(84) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000016047 (Evidence)
Ensembl Gene Model ENSMUSG00000078919 (Evidence)
Entrez Gene 13480 (Evidence)
UniGene 422657
DFCI TC1576499
Consensus CDS Project CCDS17109.1
International Mouse Phenotyping Consortium Status Dpm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016047 VEGA Gene Model | MGI Sequence Detail 21544 C57BL/6J ±  kb
transcript OTTMUST00000038290 VEGA | MGI Sequence Detail 2293 Not Applicable 
polypeptide OTTMUSP00000017164 VEGA | MGI Sequence Detail 260 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(2)
Polymorphisms
SNPs within 2kb(56 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000006656 dolichol-phosphate mannosyltransferase
References
(Earliest) J:50821 Tomita S, et al., A homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for synthesis of dolichol-phosphate-mannose in mammalian cells. J Biol Chem. 1998 Apr 10;273(15):9249-54
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)
Other
accession IDs
MGI:2138839, MGI:2138855

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory