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Dpm2
Gene Detail
 Symbol
Name
ID
Dpm2
dolichol-phosphate (beta-D) mannosyltransferase 2
MGI:1330238
Feature Type protein coding gene
Genetic Map
Chromosome 2
22.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:32570858-32573579 bp, + strand
From VEGA annotation of GRCm38

  2722 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:99726  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Dpm2

Human
homologs
Human Homolog DPM2, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
NCBI Gene ID 8818
neXtProt AC  NX_O94777
Human Synonyms  CDG1U
Human Chr (Location)  9q34.13; chr9:127935095-127938484 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human DPM2
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(8) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dpm2 interacts with 134 markers (Mir15a, Mir22, Mir27b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process dolichol metabolic process, GPI anchor biosynthetic process, ...
Component dolichol-phosphate-mannose synthase complex, endoplasmic reticulum, ...
Function dolichyl-phosphate beta-D-mannosyltransferase activity, enzyme regulator activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(78)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(80) cDNA(80)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000011991 (Evidence)
Ensembl Gene ModelENSMUSG00000026810 (Evidence)
Entrez Gene13481 (Evidence)
UniGene22001
DFCITC1576541
NIA Mouse Gene IndexU001623
Consensus CDS ProjectCCDS38104.1
International Mouse Knockout Project StatusDpm2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011991 VEGA Gene Model | MGI Sequence Detail 2722 C57BL/6J ±  kb
transcript OTTMUST00000028376 VEGA | MGI Sequence Detail 1412 Not Applicable 
polypeptide OTTMUSP00000047627 VEGA | MGI Sequence Detail 114 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(24 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009914 Dolichol phosphate-mannose biosynthesis regulatory
Protein Ontology PR:000006657 dolichol phosphate-mannose biosynthesis regulatory protein
References (Earliest) J:50812 Maeda Y, et al., DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate. EMBO J. 1998 Sep 1;17(17):4920-9
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(34)
Other
accession IDs
MGI:2139402, MGI:2139545

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory