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Dpm2
Gene Detail
Symbol

Name
ID
Dpm2
dolichol-phosphate (beta-D) mannosyltransferase 2
MGI:1330238
Feature Type
protein coding gene
Genetic Map
Chromosome 2
22.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:32570858-32575097 bp, + strand
From VEGA annotation of GRCm38

  4240 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:99726  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DPM2
Gene Tree: Dpm2

Human
homologs
DPM2, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8818
neXtProt AC: NX_O94777

Human Synonyms: CDG1U

Human Chr (Location): 9q34.13; chr9:127935095-127938484 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DPM2

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(8) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dpm2 interacts with 134 markers (Mir15a, Mir22, Mir27b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(78)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dpm2    NEW 
Molecular
reagents
All nucleic(80) cDNA(80)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000011991 (Evidence)
Ensembl Gene Model ENSMUSG00000026810 (Evidence)
Entrez Gene 13481 (Evidence)
UniGene 22001
DFCI TC1576541
NIA Mouse Gene Index U001623
Consensus CDS Project CCDS38104.1
International Mouse Phenotyping Consortium Status Dpm2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011991 VEGA Gene Model | MGI Sequence Detail 4240 C57BL/6J ±  kb
transcript OTTMUST00000028376 VEGA | MGI Sequence Detail 1412 Not Applicable 
polypeptide OTTMUSP00000047627 VEGA | MGI Sequence Detail 114 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(25 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009914 Dolichol phosphate-mannose biosynthesis regulatory
Protein Ontology PR:000006657 dolichol phosphate-mannose biosynthesis regulatory protein
References
(Earliest) J:50812 Maeda Y, et al., DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate. EMBO J. 1998 Sep 1;17(17):4920-9
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(34)
Other
accession IDs
MGI:2139402, MGI:2139545

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory