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Gabre Gene Detail
Summary
  • Symbol
    Gabre
  • Name
    gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330235
    NCBI Gene: 14404
  • Gene Overview
    MyGene.info: GABRE
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:72256926-72274822 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    67 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330235
protein coding gene ChrX:72255999-72274822 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035791
protein coding gene ChrX:67928905-67947700 (-)
A/J MGP_AJ_G0035775
protein coding gene ChrX:68165316-68182621 (-)
AKR/J MGP_AKRJ_G0035697
protein coding gene ChrX:70002511-70021300 (-)
BALB/cJ MGP_BALBcJ_G0035762
protein coding gene ChrX:67190831-67209596 (-)
C3H/HeJ MGP_C3HHeJ_G0035465
protein coding gene ChrX:68440059-68458848 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036292
protein coding gene ChrX:70010654-70029457 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033139
protein coding gene ChrX:67360233-67378982 (-)
CAST/EiJ MGP_CASTEiJ_G0034757
protein coding gene ChrX:53814596-53833370 (-)
CBA/J MGP_CBAJ_G0035440
protein coding gene ChrX:71931136-71949925 (-)
DBA/2J MGP_DBA2J_G0035593
protein coding gene ChrX:67635959-67654755 (-)
FVB/NJ MGP_FVBNJ_G0035544
protein coding gene ChrX:66986879-67005684 (-)
LP/J MGP_LPJ_G0035682
protein coding gene ChrX:68779078-68797801 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035579
protein coding gene ChrX:74510843-74529632 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036313
protein coding gene ChrX:67792430-67811225 (-)
PWK/PhJ MGP_PWKPhJ_G0034457
protein coding gene ChrX:51824832-51843993 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034292
protein coding gene ChrX:54709089-54727935 (-)
WSB/EiJ MGP_WSBEiJ_G0034899
protein coding gene ChrX:67109281-67128055 (-)



Homology
more
  • Human Ortholog
    GABRE, gamma-aminobutyric acid type A receptor epsilon subunit
  • Human Ortholog
    GABRE, gamma-aminobutyric acid type A receptor epsilon subunit
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 2564
    neXtProt AC: NX_P78334
    UniProt: P78334

  • Chr Location
    Xq28; chrX:151953124-151974679 (-)  GRCh38.p7

  • HCOP
    human homology predictions: GABRE
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14404 NCBI Gene Model | MGI Sequence Detail 17897 C57BL/6J ±  kb
transcript NM_017369 RefSeq | MGI Sequence Detail 2791 Not Specified  
polypeptide NP_059065 RefSeq | MGI Sequence Detail 916 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR008099 Gamma-aminobutyric-acid A receptor epsilon subunit
    IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
    IPR006201 Neurotransmitter-gated ion-channel
    IPR018000 Neurotransmitter-gated ion-channel, conserved site
    IPR006202 Neurotransmitter-gated ion-channel ligand-binding domain
    IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamily
    IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
    IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamily
Molecular
Reagents
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  • All nucleic 7
    cDNA 5
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:52383 Tobet SA, et al., Special relationship of gamma-aminobutyric acid to the ventromedial nucleus of the hypothalamus during embryonic development. J Comp Neurol. 1999 Mar 1;405(1):88-98
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory