About   Help   FAQ
Cldn3
Gene Detail
Symbol

Name
ID
Cldn3
claudin 3
MGI:1329044
Synonyms
Cpetr2
Feature Type
protein coding gene
Genetic Map
Chromosome 5
74.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr5:134986214-134987472 bp, + strand
From VEGA annotation of GRCm38

  1259 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1001  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog; 3 zebrafish

Gene Tree: Cldn3

Human
homologs
Human Homolog CLDN3, claudin 3
NCBI Gene ID 1365
neXtProt AC  NX_O15551
Human Synonyms  C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
Human Chr (Location)  7q11.23; chr7:73768997-73770270 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Genomic Mutations involving Cldn3 (1)
Alleles Annotated to Human Diseases(1)   
Interactions
Cldn3 interacts with 35 markers (Mir17, Mir20a, Mir20b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (23 records)
Data Summary: Results (126)    Tissues (58)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 9
RNA in situ 99
Western blot 1
RT-PCR 17
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) Genomic(4) cDNA(15) Primer pair(4)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000022612 (Evidence)
Ensembl Gene ModelENSMUSG00000070473 (Evidence)
Entrez Gene12739 (Evidence)
Consensus CDS ProjectCCDS19729.1
International Mouse Knockout Project StatusCldn3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022612 VEGA Gene Model | MGI Sequence Detail 1259 C57BL/6J ±  kb
transcript OTTMUST00000054156 VEGA | MGI Sequence Detail 1259 Not Applicable 
polypeptide OTTMUSP00000025806 VEGA | MGI Sequence Detail 219 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(5)
Polymorphisms
PCR(2) : SNPs within 2kb(20 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006187 Claudin
InterPro IPR003549 Claudin-3
InterPro IPR017974 Claudin, conserved site
InterPro IPR004031 PMP-22/EMP/MP20/Claudin
Protein Ontology PR:000005551 claudin-3
References
(Earliest) J:52002 Paperna T, et al., Genes for the CPE receptor (CPETR1) and the human homolog of RVP1 (CPETR2) are localized within the Williams-Beuren syndrome deletion. Genomics. 1998 Dec 15;54(3):453-9
(Latest) J:210656 Chakraborty P, et al., Androgen-dependent sertoli cell tight junction remodeling is mediated by multiple tight junction components. Mol Endocrinol. 2014 Jul;28(7):1055-72
All references(65)
Other
accession IDs
MGI:2140814

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory