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Rngtt Gene Detail
Summary
  • Symbol
    Rngtt
  • Name
    RNA guanylyltransferase and 5'-phosphatase
  • Synonyms
    mouse capping enzyme
  • Feature Type
    protein coding gene
  • IDs
    MGI:1329041
    NCBI Gene: 24018
  • Gene Overview
    MyGene.info: RNGTT
Location & Maps
more
  • Sequence Map
    Chr4:33310311-33502614 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      192304 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 14.78 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RNGTT, RNA guanylyltransferase and 5'-phosphatase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RNGTT, RNA guanylyltransferase and 5'-phosphatase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CAP1A, hCAP, HCE, HCE1
  • Links
    NCBI Gene ID: 8732
    neXtProt AC: NX_O60942

  • Chr Location
    6q15; chr6:88609897-88963716 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    35
  • Chemically and radiation induced
    1
  • Gene trapped
    32
  • Targeted
    2
  • Genomic Mutations
    1 involving Rngtt
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004938 VEGA Gene Model | MGI Sequence Detail 192304 C57BL/6J ±  kb
transcript OTTMUST00000010987 VEGA | MGI Sequence Detail 4157 Not Applicable  
polypeptide OTTMUSP00000005131 VEGA | MGI Sequence Detail 597 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    502 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140461
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:50704 McCracken S, et al., 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II [see comments]. Genes Dev. 1997 Dec 15;11(24):3306-18
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory