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Mllt10
Gene Detail
Symbol

Name
ID
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MGI:1329038
Synonyms
Af10, B130021D15Rik, D630001B22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
12.84 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:18064394-18212388 bp, + strand
From VEGA annotation of GRCm38

  147995 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20973  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Mllt10

Human
homologs
Human Homolog MLLT10, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NCBI Gene ID 8028
neXtProt AC  NX_P55197
Human Synonyms  AF10
Human Chr (Location)  10p12; chr10:21534172-21743630 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(141) : Gene trapped(137) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mllt10 interacts with 327 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process positive regulation of transcription from RNA polymerase II promoter
Component cytoplasm, nucleus
Function metal ion binding, zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (67)    Tissues (67)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 59
RT-PCR 8
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(24) Genomic(2) cDNA(21) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000011456 (Evidence)
Ensembl Gene ModelENSMUSG00000026743 (Evidence)
Entrez Gene17354 (Evidence)
Consensus CDS ProjectCCDS15708.1, CCDS57155.1
International Mouse Knockout Project StatusMllt10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011456 VEGA Gene Model | MGI Sequence Detail 147995 C57BL/6J ±  kb
transcript OTTMUST00000026949 VEGA | MGI Sequence Detail 3543 Not Applicable 
polypeptide OTTMUSP00000012295 VEGA | MGI Sequence Detail 1068 Not Applicable 

For the selected sequences
All sequences(114) RefSeq(51) UniProt(11)
Polymorphisms
SNPs within 2kb(302 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000010450 protein AF-10
References
(Earliest) J:51922 Linder B, et al., Expression pattern and cellular distribution of the murine homologue of AF10. Biochim Biophys Acta. 1998 Dec 22;1443(3):285-96
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGI:2443668, MGI:2443937

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory