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Ccl20 Gene Detail
Summary
  • Symbol
    Ccl20
  • Name
    chemokine (C-C motif) ligand 20
  • Synonyms
    CKb4, exodus-1, MIP-3[a], MIP3A, MIP-3A, Scya20, ST38
  • Feature Type
    protein coding gene
  • IDs
    MGI:1329031
    NCBI Gene: 20297
  • Gene Overview
    MyGene.info: CCL20
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:83116766-83119167 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 42.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1329031
protein coding gene Chr1:83116766-83119167 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016223
protein coding gene Chr1:84082927-84085328 (+)
A/J MGP_AJ_G0016206
protein coding gene Chr1:81092582-81094983 (+)
AKR/J MGP_AKRJ_G0016163
protein coding gene Chr1:83297748-83300149 (+)
BALB/cJ MGP_BALBcJ_G0016161
protein coding gene Chr1:81242269-81244670 (+)
C3H/HeJ MGP_C3HHeJ_G0015991
protein coding gene Chr1:83677792-83680193 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016614
protein coding gene Chr1:87332459-87334860 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014334
protein coding gene Chr1:76287238-76289689 (+)
CAST/EiJ MGP_CASTEiJ_G0015576
protein coding gene Chr1:83107932-83110337 (+)
CBA/J MGP_CBAJ_G0015965
protein coding gene Chr1:90125718-90128119 (+)
DBA/2J MGP_DBA2J_G0016066
protein coding gene Chr1:80362148-80364591 (+)
FVB/NJ MGP_FVBNJ_G0016069
protein coding gene Chr1:79479515-79481916 (+)
LP/J MGP_LPJ_G0016139
protein coding gene Chr1:85194779-85197180 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016089
protein coding gene Chr1:93486560-93489408 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016661
protein coding gene Chr1:83476894-83479295 (+)
PWK/PhJ MGP_PWKPhJ_G0015362
protein coding gene Chr1:79819772-79822177 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015140
protein coding gene Chr1:82667941-82670343 (+)
WSB/EiJ MGP_WSBEiJ_G0015637
protein coding gene Chr1:83262304-83264705 (+)



Homology
more
  • Human Ortholog
    CCL20, C-C motif chemokine ligand 20
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CCL20, C-C motif chemokine ligand 20
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CKb4, Exodus, LARC, MIP-3a, MIP3A, MIP-3-alpha, SCYA20, ST38
  • Links
    NCBI Gene ID: 6364
    neXtProt AC: NX_P78556
    UniProt: P78556

  • Chr Location
    2q36.3; chr2:227813842-227817564 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20297 NCBI Gene Model | MGI Sequence Detail 2402 C57BL/6J ±  kb
transcript NM_016960 RefSeq | MGI Sequence Detail 852 C57BL/6  
polypeptide O89093 UniProt | EBI | MGI Sequence Detail 97 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • PDB
  • InterPro Domains
    IPR000827 CC chemokine, conserved site
    IPR034133 Chemokine CC, DCCL motif-cointaining domain
    IPR001811 Chemokine interleukin-8-like domain
    IPR036048 Chemokine interleukin-8-like superfamily
Molecular
Reagents
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  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 56
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:250695 Dutta P, et al., Biphasic Ccl20 regulation by Toll-like receptor 9 through the activation of ERK-AP-1 and non-canonical NF-kappaB signaling pathways. Biochim Biophys Acta. 2017 Jan;1861(1 Pt A):3365-3377

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory