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Galr3 Gene Detail
Summary
  • Symbol
    Galr3
  • Name
    galanin receptor 3
  • Synonyms
    Galnr3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1329003
    NCBI Gene: 14429
  • Gene Overview
    MyGene.info: GALR3
Location & Maps
more
  • Sequence Map
    Chr15:79041885-79043558 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1674 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    GALR3, galanin receptor 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    GALR3, galanin receptor 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 8484
    neXtProt AC: NX_O60755

  • Chr Location
    22q13.1; chr22:37822009-37825865 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 2 genetic backgrounds
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Galr3
  • Incidental Mutations
Mice homozygous for a null allele exhibit increased anxiety-like behavior and abnormal social investigation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14429 NCBI Gene Model | MGI Sequence Detail 1674 C57BL/6J ±  kb
transcript NM_015738 RefSeq | MGI Sequence Detail 1245 Not Specified  
polypeptide NP_056553 RefSeq | MGI Sequence Detail 370 Not Specified  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    5 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 21
  • Earliest
    J:56036 Southard-Smith EM, et al., Comparative analyses of the Dominant megacolon-SOX10 genomic interval in mouse and human. Mamm Genome. 1999 Jul;10(7):744-9
  • Latest
    J:211066 Brunner SM, et al., GAL3 receptor KO mice exhibit an anxiety-like phenotype. Proc Natl Acad Sci U S A. 2014 May 13;111(19):7138-43

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory