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Ccnt1 Gene Detail
Summary
  • Symbol
    Ccnt1
  • Name
    cyclin T1
  • Synonyms
    2810478G24Rik, CycT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328363
    NCBI Gene: 12455
  • Gene Overview
    MyGene.info: CCNT1
Location & Maps
more
  • Sequence Map
    Chr15:98538689-98570923 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      32235 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 54.54 cM, cytoband F2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CCNT1, cyclin T1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CCNT1, cyclin T1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCNT, CYCT1, HIVE1
  • Links
    NCBI Gene ID: 904
    neXtProt AC: NX_O60563

  • Chr Location
    12q13.11; chr12:48688458-48716998 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    28 phenotype references
  • All Mutations and Alleles
    17
  • Chemically induced (other)
    1
  • Gene trapped
    13
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Ccnt1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035789 VEGA Gene Model | MGI Sequence Detail 32235 C57BL/6J ±  kb
transcript OTTMUST00000091602 VEGA | MGI Sequence Detail 7397 Not Applicable  
polypeptide OTTMUSP00000050470 VEGA | MGI Sequence Detail 724 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    205 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 5
Other
Accession IDs
less
MGI:1920080, MGI:2145948
References
more
  • Summaries
    All 54
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 10
    Phenotypes 28
  • Earliest
    J:51312 Garber ME, et al., The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes Dev. 1998 Nov 15;12(22):3512-27
  • Latest
    J:192997 Dai Q, et al., Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells. J Biol Chem. 2012 Jul 20;287(30):25344-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory